Saga T, Akita N, Tomoyori H, Matsuda H, Isu T
Department of Ophthalmology, Hokkaido University School of Medicine, Japan.
Jpn J Ophthalmol. 1990;34(1):30-5.
Hemifacial spasm can cause abnormal tear secretion on the affected side. Thirty patients with this disease were examined using the Schirmer's test without topical anesthetic. Twelve of them showed more tear secretion on the affected side than on the unaffected side. The average Schirmer test value was 30.4 +/- 12.3 mm (+/- SD) on the affected side in the patients and 17.4 +/- 10.9 mm (n = 148) in the control subjects (P less than 0.001). Microvascular decompression surgery reduced the hypersecretion of tears. The results suggest that compression of the facial nerve by a blood vessel causes an excitatory stimulus for tear secretion in patients with hemifacial spasm.
面肌痉挛可导致患侧泪液分泌异常。对30例该疾病患者在未使用表面麻醉剂的情况下进行了Schirmer试验检查。其中12例患者患侧泪液分泌多于未患侧。患者患侧Schirmer试验平均值为30.4±12.3毫米(±标准差),而对照组为17.4±10.9毫米(n = 148)(P<0.001)。微血管减压手术减少了泪液的过度分泌。结果表明,血管对面神经的压迫在面肌痉挛患者中引起了泪液分泌的兴奋性刺激。