Cardiology Unit, Internal Medicine Department, Salmaniya Medical Complex, PO Box 12, Manama, Kingdom of Bahrain.
Clin Res Cardiol. 2013 Aug;102(8):593-8. doi: 10.1007/s00392-013-0570-5. Epub 2013 Apr 28.
To study the clinical significance of presenting blood pressure parameters and heart rate in patients with hypertensive crisis.
In patients admitted with hypertensive crisis between January 2011 and May 2011, demography, mode of presentation, co-morbidities, blood pressure readings, and heart rate at presentation were documented. Further clustering of hypertensive crisis into emergency or urgency was based on the presence or absence of target organ involvement. The relationship between blood pressure parameters, heart rate, and other variables was analyzed.
189 patients in sinus rhythm were enrolled in this pilot study. The rate of hypertensive urgency was 56 %, whereas the rate of hypertensive emergency was 44 %, respectively. Subjects with hypertensive emergency had a higher mean heart rate (93 ± 22.7 bpm) than those with urgency (81 ± 11.5 bpm) (P = 0.015). Women had higher heart rates (92 ± 18.5 bpm) than men (86 ± 17.6 bpm) (P = 0.014). Heart rates below 100 bpm had a specificity of 94 %, classifying patients as hypertensive urgency. Tachycardia had a powerful statistical association with hypertensive left ventricular failure (P < 0.0001). Other hemodynamic parameters, including systolic blood pressure, diastolic blood pressure, pulse pressure, and mean blood pressure relates neither to urgency nor to emergency. Diabetic patients with HBA1c levels of more than 53 mmol/mol had a heart rate of more than 100 bpm (P = 0.015) during hypertensive crisis.
Normal heart rate is characteristic of hypertensive urgency. Tachycardia in this setting is an ominous sign and denotes hypertensive complications in particular left ventricular failure. Among diabetics, elevated heart rate is associated with poor glycemic control.
研究高血压危象患者血压参数和心率的临床意义。
在 2011 年 1 月至 2011 年 5 月期间因高血压危象入院的患者中,记录人口统计学特征、表现方式、合并症、就诊时的血压读数和心率。进一步根据是否存在靶器官受累将高血压危象分为紧急和紧急情况。分析血压参数、心率与其他变量之间的关系。
本初步研究纳入了 189 例窦性节律患者。高血压急症的发生率为 56%,而高血压紧急情况的发生率为 44%。高血压急症患者的平均心率(93±22.7bpm)高于紧急情况(81±11.5bpm)(P=0.015)。女性的心率(92±18.5bpm)高于男性(86±17.6bpm)(P=0.014)。心率低于 100bpm 时,特异性为 94%,可将患者归类为高血压急症。心动过速与高血压左心室衰竭有很强的统计学关联(P<0.0001)。其他血流动力学参数,包括收缩压、舒张压、脉压和平均血压,既与紧急情况无关,也与紧急情况无关。糖化血红蛋白水平大于 53mmol/mol 的糖尿病患者在高血压危象期间心率大于 100bpm(P=0.015)。
正常心率是高血压急症的特征。在这种情况下的心动过速是一个不祥的迹象,表明存在高血压并发症,特别是左心室衰竭。在糖尿病患者中,心率升高与血糖控制不佳有关。