Defining miRNA targets: balancing simplicity with complexity.
作者信息
Freedman Jane E, Tanriverdi Kahraman
出版信息
Circulation. 2013 May 28;127(21):2075-7. doi: 10.1161/CIRCULATIONAHA.113.003058. Epub 2013 Apr 26.
Abstract
摘要
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本文引用的文献
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MiR-378 controls cardiac hypertrophy by combined repression of mitogen-activated protein kinase pathway factors.miR-378 通过共同抑制有丝分裂原激活蛋白激酶通路因子来控制心肌肥大。
Circulation. 2013 May 28;127(21):2097-106. doi: 10.1161/CIRCULATIONAHA.112.000882. Epub 2013 Apr 26.
2
A cardiac-enriched microRNA, miR-378, blocks cardiac hypertrophy by targeting Ras signaling.一种心脏富集的 microRNA，miR-378，通过靶向 Ras 信号通路抑制心脏肥大。
J Biol Chem. 2013 Apr 19;288(16):11216-32. doi: 10.1074/jbc.M112.442384. Epub 2013 Feb 27.
3
MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles.用于心血管疾病的 microRNA 治疗学：机遇与障碍。
Nat Rev Drug Discov. 2012 Nov;11(11):860-72. doi: 10.1038/nrd3864. Epub 2012 Oct 19.
4
Global microRNA profiling of the mouse ventricles during development of severe hypertrophic cardiomyopathy and heart failure.在严重肥厚型心肌病和心力衰竭发展过程中，小鼠心室的全球 microRNA 谱分析。
PLoS One. 2012;7(9):e44744. doi: 10.1371/journal.pone.0044744. Epub 2012 Sep 14.
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Developing microRNA therapeutics: approaching the unique complexities.开发 microRNA 治疗药物：应对独特的复杂性。
Nucleic Acid Ther. 2012 Aug;22(4):213-25. doi: 10.1089/nat.2012.0356.
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Mol Syst Biol. 2012 Feb 14;8:570. doi: 10.1038/msb.2011.100.
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miRNAs versus oncogenes: the power of social networking.微小RNA与癌基因：社交网络的力量
Mol Syst Biol. 2012 Feb 14;8:569. doi: 10.1038/msb.2012.2.
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Developing microRNA therapeutics.开发 microRNA 疗法。
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Overexpression of microRNA-378 attenuates ischemia-induced apoptosis by inhibiting caspase-3 expression in cardiac myocytes.microRNA-378 的过表达通过抑制心肌细胞中 caspase-3 的表达来减轻缺血诱导的细胞凋亡。
Apoptosis. 2012 Apr;17(4):410-23. doi: 10.1007/s10495-011-0683-0.
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MicroRNAs involved in the mitogen-activated protein kinase cascades pathway during glucose-induced cardiomyocyte hypertrophy.葡萄糖诱导心肌细胞肥大过程中丝裂原活化蛋白激酶级联途径相关的 microRNAs。
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