Pediatric Cardiac Anesthesia/Intensive Care Unit, Department of Pediatric Cardiology and Cardiac Surgery, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Nephrol Dial Transplant. 2013 Sep;28(9):2211-4. doi: 10.1093/ndt/gft074. Epub 2013 Apr 25.
A standardized classification of acute kidney injury (AKI) has recently been proposed with the RIFLE (Risk, Injury, Failure, Loss of function, End-stage kidney disease) score. Such definition/classification has been applied both in adult and in paediatric patients. Neonatal definition of AKI likely results as a challenging task due to the peculiar renal pathophysiology of newborn critically ill patients. Their so-called 'immature kidneys' require careful management and neonatal AKI is frequently complicated by unfavourable outcomes. A recent attempt to implement the RIFLE score with a neonatal modification might lead to improvement on the knowledge of AKI incidence and epidemiology.
最近提出了一种急性肾损伤 (AKI) 的标准化分类，采用了 RIFLE（风险、损伤、衰竭、功能丧失和终末期肾病）评分。这种定义/分类已应用于成人和儿科患者。由于新生儿重症患者的特殊肾脏生理学，新生儿 AKI 的定义可能是一项具有挑战性的任务。他们所谓的“不成熟的肾脏”需要谨慎处理，新生儿 AKI 常伴有不良结局。最近尝试使用新生儿改良版实施 RIFLE 评分可能会提高对 AKI 发生率和流行病学的认识。
