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自体血小板在黄斑裂孔手术中的疗效。

Efficacy of autologous platelets in macular hole surgery.

作者信息

Konstantinidis Aristeidis, Hero Mark, Nanos Panagiotis, Panos Georgios D

机构信息

Department of Ophthalmology, University Hospital of Alexandroupolis, Alexandroupolis, Greece ; Opthalmology Department, University Hospital Coventry and Warwickshire, Coventry, UK.

出版信息

Clin Ophthalmol. 2013;7:745-50. doi: 10.2147/OPTH.S44440. Epub 2013 Apr 17.

DOI:10.2147/OPTH.S44440
PMID:23626459
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3632626/
Abstract

The introduction of optical coherence tomography has allowed accurate measurement of the size of macular holes. A retrospective consecutive review was performed of 21 patients undergoing macular hole repair with vitrectomy, gas tamponade, and autologous platelet injection and we assessed the effect of macular hole parameters on anatomic and functional outcomes. We looked at the demographic features, final visual outcome, and anatomical closure. Twenty-one patients were included in the study. They underwent routine vitrectomy with gas tamponade (C3F8) and injection of autologous platelets. All patients were advised to maintain a facedown posture for 2 weeks. Anatomical closure was confirmed in all cases and 20 out of 21 of patients had improved postoperative visual acuity by two or more lines. In our series, the macular hole dimensions did not have much effect on the final results. The use of autologous platelets and strict facedown posture seems to be the deciding factor in good anatomical and visual outcome irrespective of macular hole dimensions.

摘要

光学相干断层扫描技术的引入使得黄斑裂孔大小的精确测量成为可能。我们对21例行玻璃体切除术、气体填塞及自体血小板注射进行黄斑裂孔修复的患者进行了回顾性连续研究,并评估了黄斑裂孔参数对解剖和功能结果的影响。我们观察了人口统计学特征、最终视力结果及解剖学上的闭合情况。21例患者纳入研究。他们接受了常规的玻璃体切除术、气体填塞(C3F8)及自体血小板注射。所有患者均被建议保持俯卧位2周。所有病例均证实解剖学上已闭合,21例患者中有20例术后视力提高了两行或更多。在我们的系列研究中,黄斑裂孔尺寸对最终结果影响不大。无论黄斑裂孔尺寸如何,使用自体血小板及严格的俯卧位似乎是获得良好解剖和视力结果的决定性因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb28/3632626/0f39845fd84e/opth-7-745Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb28/3632626/0f39845fd84e/opth-7-745Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb28/3632626/0f39845fd84e/opth-7-745Fig1.jpg

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2
Macular hole surgery prognostic success rates based on macular hole size.基于黄斑裂孔大小的黄斑裂孔手术预后成功率。
Ophthalmic Surg Lasers Imaging. 2012 May-Jun;43(3):184-9. doi: 10.3928/15428877-20120102-05. Epub 2012 Feb 9.
3
Face-down positioning or posturing after macular hole surgery.
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Int Ophthalmol. 2021 Mar;41(3):1043-1052. doi: 10.1007/s10792-020-01662-4. Epub 2021 Jan 3.
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Int J Retina Vitreous. 2020 Sep 21;6:43. doi: 10.1186/s40942-020-00248-7. eCollection 2020.
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