Butikofer Scott, Dettori Jason M, Vemulakonda G Atma, Slabaugh Mark
University of Washington School of Medicine, University of Washington, Seattle, Wash., USA.
Case Rep Ophthalmol. 2013 Mar 7;4(1):42-5. doi: 10.1159/000350270. Print 2013 Jan.
We report a positive outcome of postcataract endophthalmitis caused by Enterobacter cloacae, which has previously resulted in poor outcomes in endophthalmitis. A 67-year-old man underwent uncomplicated cataract surgery. On the morning of postoperative day (POD) #1, he had significant anterior chamber inflammation without pain, hypopyon, or vitritis but then rapidly developed hypopyon and worsening visual acuity. He underwent a tap and inject with vancomycin and ceftazidime and was prescribed topical steroids and antibiotics as well as oral levofloxacin. On POD #3, cultures of the vitreous and aqueous returned positive for E. cloacae. By POD #6, his hypopyon had resolved with improved vitritis, decreased inflammation, and visual acuity of 20/200. Two weeks after surgery, his best-corrected visual acuity was 20/60. Contrary to prior reports, we demonstrate that it is possible to achieve a good outcome in cases of E. cloacae endophthalmitis treated early with appropriate antibiotics and anti-inflammatory agents.
我们报告了一例由阴沟肠杆菌引起的白内障术后眼内炎的良好治疗结果,而此前该菌导致的眼内炎预后较差。一名67岁男性接受了无并发症的白内障手术。术后第1天早晨,他出现明显的前房炎症,但无疼痛、前房积脓或玻璃体炎,随后迅速出现前房积脓且视力恶化。他接受了玻璃体腔穿刺注药,注射了万古霉素和头孢他啶,并给予局部类固醇和抗生素以及口服左氧氟沙星治疗。术后第3天,玻璃体和房水培养结果显示阴沟肠杆菌呈阳性。到术后第6天,他的前房积脓消退,玻璃体炎改善,炎症减轻,视力为20/200。术后两周,他的最佳矫正视力为20/60。与先前的报道相反,我们证明,对于早期用适当的抗生素和抗炎药治疗的阴沟肠杆菌性眼内炎病例,有可能取得良好的治疗结果。