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一种存在于患有睑缘炎的大型狐蝠(马来大狐蝠)体内的新型γ疱疹病毒。

A novel gammaherpesvirus in a large flying fox (Pteropus vampyrus) with blepharitis.

作者信息

Paige Brock A, Cortés-Hinojosa Galaxia, Plummer Caryn E, Conway Julia A, Roff Shannon R, Childress April L, Wellehan James F X

机构信息

Department of Small Animal Clinical Sciences, University of Florida, 2015 SW 16th Avenue, Gainesville, FL 32608, USA.

出版信息

J Vet Diagn Invest. 2013 May;25(3):433-7. doi: 10.1177/1040638713486645. Epub 2013 Apr 29.

Abstract

A novel gammaherpesvirus was identified in a large flying fox (Pteropus vampyrus) with conjunctivitis, blepharitis, and meibomianitis by nested polymerase chain reaction and sequencing. Polymerase chain reaction amplification and sequencing of 472 base pairs of the DNA-dependent DNA polymerase gene were used to identify a novel herpesvirus. Bayesian and maximum likelihood phylogenetic analyses indicated that the virus is a member of the genus Percavirus in the subfamily Gammaherpesvirinae. Additional research is needed regarding the association of this virus with conjunctivitis and other ocular pathology. This virus may be useful as a biomarker of stress and may be a useful model of virus recrudescence in Pteropus spp.

摘要

通过巢式聚合酶链反应和测序,在一只患有结膜炎、睑缘炎和睑板腺炎的大型狐蝠(马来大狐蝠)中鉴定出一种新型伽马疱疹病毒。利用依赖DNA的DNA聚合酶基因472个碱基对的聚合酶链反应扩增和测序来鉴定一种新型疱疹病毒。贝叶斯和最大似然系统发育分析表明,该病毒是伽马疱疹病毒亚科中Percavirus属的成员。关于这种病毒与结膜炎和其他眼部病理学的关联,还需要进一步研究。这种病毒可能作为应激的生物标志物有用,并且可能是狐蝠属中病毒复发的有用模型。

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