Suzuki Akitake, Shoji Norikazu, Kikuchi Eigo, Uekubo Kazuaki, Aoki Naoko, Sonoda Yui, Torigai Hideyuki, Yamashita Hiroyuki, Fujita Kentaro, Okai Takahiro
Center for Rheumatology and Joint Surgery, Kawakita General Hospital.
Nihon Rinsho Meneki Gakkai Kaishi. 2013;36(2):122-8. doi: 10.2177/jsci.36.122.
We report three patients with dermatomyositis (DM) complicated with acute interstitial pneumonia (AIP). All of them complained of fever and acutely worsening dyspnea and were treated immediately by combination therapies with pulse therapy with methylprednisone (mPSL) followed by corticosteroids, biweekly intravenous pulse cyclophosphamide (IVCY) and cyclosporine A (CSA). They recovered rapidly soon after an initiation of this combination regimen. Early intervention with aggressive combination therapy is life-saving for the treatment of AIP in patients with DM.
我们报告了3例皮肌炎（DM）合并急性间质性肺炎（AIP）的患者。他们均主诉发热和急性加重的呼吸困难，并立即接受了联合治疗，包括甲泼尼龙（mPSL）冲击治疗后序贯使用糖皮质激素、每两周一次的静脉环磷酰胺（IVCY）冲击治疗以及环孢素A（CSA）治疗。在开始这种联合治疗方案后不久，他们均迅速康复。对于DM合并AIP患者，早期采用积极的联合治疗进行干预可挽救生命。
