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[经巩膜睫状体光凝术作为青光眼的主要手术干预措施]

[Transscleral cyclophotocoagulation as primary surgical intervention in glaucoma].

作者信息

Winkler N F K, Funk J

机构信息

University Hospital Zurich, Division of Ophthalmology, Zurich, Switzerland.

出版信息

Klin Monbl Augenheilkd. 2013 Apr;230(4):353-7. doi: 10.1055/s-0032-1328359. Epub 2013 Apr 29.

DOI:10.1055/s-0032-1328359
PMID:23629778
Abstract

BACKGROUND

The gold standard of surgical interventions in medically uncontrolled glaucoma is trabeculectomy. Cyclophotocoagulation is often performed only as a secondary/tertiary surgery. Since trabeculectomy demands a high degree of postsurgical compliance to achieve satisfying results, some patients do not qualify for trabeculectomy.

PATIENTS AND METHODS

During cyclophotocoagulation, the ciliary processes were coagulated using a transscleral diode laser. 49 eyes of 47 patients (25 women and 22 men) were included in our study. Patients were regularly followed up for 24 months. During follow-up, IOP, best corrected visual acuity and number of antiglaucoma drugs were recorded.

RESULTS

The mean age was 69.27 ± 14.45 years. The diagnosis was open-angle glaucoma in 15 eyes, pseudoexfoliative glaucoma in 12 eyes, secondary rubeotic glaucoma in 7 eyes and secondary glaucoma without further specification in 15 eyes. On average, cyclophotocoagulation reduced intraocular pressure by 14.45 ± 11.77 mmHg (-42.7%, p < 0.001). Medication could be reduced by 1.31 ± 1.27 (-52%, p < 0.001). On average, visual acuity deteriorated by 0.383 LogMAR (± 0.848, p = 0.004).

CONCLUSION

For selected glaucoma patients, cyclophotocoagulation could be an option as primary surgical intervention to lower intraocular pressure.

摘要

背景

药物治疗无法控制的青光眼手术干预的金标准是小梁切除术。睫状体光凝术通常仅作为二级/三级手术进行。由于小梁切除术需要高度的术后依从性才能取得满意的效果,一些患者不符合小梁切除术的条件。

患者与方法

在睫状体光凝术中,使用经巩膜二极管激光凝固睫状体。我们的研究纳入了47例患者(25名女性和22名男性)的49只眼。对患者进行了为期24个月的定期随访。随访期间,记录眼压、最佳矫正视力和抗青光眼药物的使用数量。

结果

平均年龄为69.27±14.45岁。诊断为开角型青光眼15眼,剥脱性青光眼12眼,继发性新生血管性青光眼7眼,未进一步明确的继发性青光眼15眼。平均而言,睫状体光凝术使眼压降低了14.45±11.77 mmHg(-42.7%,p<0.001)。药物使用量可减少1.31±1.27(-52%,p<0.001)。平均而言,视力下降了0.383 LogMAR(±0.848,p = 0.004)。

结论

对于选定的青光眼患者,睫状体光凝术可作为降低眼压的主要手术干预选择。

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