Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester Academic Health Sciences Centre, Stopford Building, Oxford Road, Manchester M13 9PT, UK.
Rheumatology (Oxford). 2013 Nov;52(11):1941-51. doi: 10.1093/rheumatology/ket150. Epub 2013 Apr 28.
There has been a concerted and important international effort to develop and validate disease activity and outcome instruments specific to JIA in recent years. This review aims to describe the disease assessment indices important to routine clinical care and integral to the design of outcome studies and clinical trials in JIA. In view of the increasing number of JIA clinical studies and clinical trials, together with a number of national and international paediatric biologic registers, it is important that knowledge of these new outcome measures is widespread, such that results can be placed in a meaningful context.
近年来，国际社会一直在齐心协力，努力开发和验证专门针对幼年特发性关节炎（JIA）的疾病活动度和结局评估工具。本综述旨在描述对常规临床护理重要、并构成 JIA 结局研究和临床试验设计基础的疾病评估指标。鉴于 JIA 的临床研究和临床试验日益增多，以及一些国家和国际儿科生物制剂注册，广泛了解这些新的结局评估指标非常重要，这样才能使研究结果有意义。
