Salman A Ebru, Yetişir Fahri, Yürekli Banu, Aksoy Mustafa, Yildirim Murat, Kiliç Mehmet
Anesthesiology and Reanimation Department.
Local Reg Anesth. 2013 Jan 18;6:1-7. doi: 10.2147/LRA.S38359. Print 2013.
In this prospective, randomized, double-blind study, our aim was to compare the analgesic efficacy of the semi-blind approach of transversus abdominis plane (TAP) block with a placebo block in patients undergoing unilateral inguinal hernia repair.
After receiving hospital ethical committee approval and informed patient consents, American Society of Anesthesiologists (ASA) I-III patients aged 18-80 were enrolled in the study. Standard anesthesia monitoring was applied to all patients. After premedication, spinal anesthesia was administered to all patients with 3.5 mL heavy bupivacaine at the L3-L4 subarachnoid space. Patients were randomly allocated into 2 groups. Group I (n = 32) received a placebo block with 20 mL saline, Group II (n = 32) received semi-blind TAP block with 0.25% bupivacaine in 20 mL with a blunt regional anesthesia needle into the neurofascial plane via the lumbar triangle of Petit near the midaxillary line before fascial closure. At the end of the operation, intravenous (IV) dexketoprofen was given to all patients. The verbal analog scale (VAS) was recorded at 2, 4, 6, 12, and 24 hours postoperatively. Paracetamol IV was given to patients if their VAS score > 3. A rescue analgesic of 0.05 mg/kg morphine IV was applied if VA S > 3. Total analgesic consumption and morphine requirement in 24 hours were recorded.
TAP block reduced VAS scores at all postoperative time points (P < 0.001). Postoperative analgesic and morphine requirement in 24 hours was significantly lower in group II (P < 0.01).
Semi-blind TAP block provided effective analgesia, reducing total 24-hour postoperative analgesic consumption and morphine requirement in patients undergoing elective unilateral inguinal hernia repair.
在这项前瞻性、随机、双盲研究中,我们的目的是比较在接受单侧腹股沟疝修补术的患者中,腹横肌平面(TAP)阻滞半盲法与安慰剂阻滞的镇痛效果。
在获得医院伦理委员会批准并取得患者知情同意后,纳入年龄在18 - 80岁的美国麻醉医师协会(ASA)I - III级患者进行研究。对所有患者进行标准麻醉监测。术前用药后,于L3 - L4蛛网膜下腔给所有患者注射3.5 mL重比重布比卡因进行脊髓麻醉。患者被随机分为2组。第一组(n = 32)接受20 mL生理盐水的安慰剂阻滞,第二组(n = 32)在筋膜关闭前,通过腋中线附近的 Petit 腰三角,使用钝头区域麻醉针将20 mL含0.25%布比卡因注入神经筋膜平面,进行半盲TAP阻滞。手术结束时,给所有患者静脉注射(IV)右酮洛芬。术后2、4、6、12和24小时记录视觉模拟评分(VAS)。如果患者VAS评分>3,则给予对乙酰氨基酚静脉注射。如果VAS>3,则应用0.05 mg/kg吗啡静脉注射进行补救镇痛。记录24小时内的总镇痛药物消耗量和吗啡需求量。
TAP阻滞在所有术后时间点均降低了VAS评分(P < 0.001)。第二组术后24小时的镇痛药物和吗啡需求量显著更低(P < 0.01)。
半盲TAP阻滞提供了有效的镇痛效果,减少了择期单侧腹股沟疝修补术患者术后24小时的总镇痛药物消耗量和吗啡需求量。