Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China;
Quant Imaging Med Surg. 2013 Apr;3(2):100-12. doi: 10.3978/j.issn.2223-4292.2013.03.03.
Prostate cancer is the most common cancer diagnosed in men and a leading cause of death. Accurate assessment is a prerequisite for optimal clinical management and therapy selection of prostate cancer. There are several parameters and nomograms to differentiate between patients with clinically insignificant disease and patients in need of treatment. Magnetic resonance imaging (MRI) is a technique which provides more detailed anatomical images due to high spatial resolution, superior contrast resolution, and multiplanar capability. State-of-the-art MRI techniques, such as diffusion weighted imaging (DWI), MR spectroscopic imaging (MRSI), dynamic contrast enhanced MRI (DCE-MRI), improve interpretation of prostate cancer imaging. In this article, we review the major role of MRI in the advanced management of prostate cancer to noninvasively improve tumor staging, biologic potential, treatment planning, therapy response, local recurrence, and to guide target biopsy for clinical suspected cancer with previous negative biopsy. Finally, future challenges and opportunities in prostate cancer management in the area of functional MRI are discussed as well.
前列腺癌是男性最常见的癌症，也是死亡的主要原因之一。准确的评估是优化前列腺癌临床管理和治疗选择的前提。有几个参数和诺莫图可以区分临床意义不大的疾病患者和需要治疗的患者。磁共振成像（MRI）是一种技术，由于具有高空间分辨率、优越的对比分辨率和多平面能力，可提供更详细的解剖图像。最先进的 MRI 技术，如扩散加权成像（DWI）、磁共振波谱成像（MRSI）、动态对比增强 MRI（DCE-MRI），可提高前列腺癌成像的解读。本文综述了 MRI 在前列腺癌高级管理中的主要作用，以无创方式改善肿瘤分期、生物学潜能、治疗计划、治疗反应、局部复发，并指导临床疑似癌症的靶向活检，此前活检为阴性。最后，还讨论了功能 MRI 在前列腺癌管理领域的未来挑战和机遇。
