Section of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
J Clin Gastroenterol. 2013 Jul;47 Suppl(0):S2-6. doi: 10.1097/MCG.0b013e3182872f29.
Hepatocellular carcinoma (HCC) is increasing in incidence and has a very high fatality rate. Cirrhosis due to chronic hepatitis B or hepatitis C is the leading risk factor for HCC. Global epidemiology of HCC is determined by the prevalence of dominant viral hepatitis and the age it is acquired in the underlying population. Upcoming risk factors include obesity, diabetes, and related nonalcoholic fatty liver disease. This review discusses the latest trends of HCC globally and in the United States. It also provides an evidence-based commentary on the risk factors and lists some of the preventive measures to reduce the incidence of HCC.
肝细胞癌(HCC)的发病率正在上升,死亡率非常高。由慢性乙型肝炎或丙型肝炎引起的肝硬化是 HCC 的主要危险因素。HCC 的全球流行病学由主要的病毒性肝炎的流行情况以及其在潜在人群中被感染的年龄决定。即将出现的危险因素包括肥胖、糖尿病和相关的非酒精性脂肪肝疾病。这篇综述讨论了 HCC 在全球和美国的最新趋势。它还提供了关于危险因素的循证评论,并列出了一些预防措施以降低 HCC 的发病率。