Zinkevich O D, Safina N A, Kharrasov A F, Mingazova A Kh
Vopr Med Khim. 1990 Mar-Apr;36(2):53-5.
Effect of some fibronectin preparations on luminol-dependent chemiluminescence of neutrophils was studied. These fibronectin preparations were obtained after heat denaturation and tryptic digestion. Native fibronectin cause aggregation of gelatin-coated particles and dose-dependent promotion of chemiluminescence of neutrophils, while the rate of these reactions was distinctly decreased if the heat denaturated preparations of fibronectin were used. Structural integrity of fibronectin molecule appears to be responsible for promotion of the neutrophil chemiluminescence.
研究了某些纤连蛋白制剂对中性粒细胞鲁米诺依赖性化学发光的影响。这些纤连蛋白制剂是经过热变性和胰蛋白酶消化后获得的。天然纤连蛋白可导致明胶包被颗粒聚集并呈剂量依赖性促进中性粒细胞化学发光，而如果使用热变性的纤连蛋白制剂，这些反应的速率则明显降低。纤连蛋白分子的结构完整性似乎是促进中性粒细胞化学发光的原因。
