Department of Internal Medicine, Slotervaartziekenhuis, Amsterdam, The Netherlands.
Semin Thromb Hemost. 2013 Jul;39(5):489-95. doi: 10.1055/s-0033-1343889. Epub 2013 Apr 30.
Endocrine diseases have been associated with cardiovascular events. Both altered coagulation and fibrinolysis markers and thrombotic disorders have been described in several endocrine diseases. This review summarizes the evidence on the influence of thyroid diseases, cortisol excess and deficiency, pheochromocytoma, hyperparathyroidism, hyperaldosteronism, hyperprolactinemia, and growth hormone excess and deficiency; on parameters of hemostasis; and on arterial and venous thrombotic events. All these endocrine diseases do have, or may have, influence either on hemostasis or on the risk of thrombotic events. Future studies are needed to establish the clinical relevance of these associations.
内分泌疾病与心血管事件有关。几种内分泌疾病中已描述了凝血和纤溶标志物的改变以及血栓形成障碍。这篇综述总结了甲状腺疾病、皮质醇过多和缺乏、嗜铬细胞瘤、甲状旁腺功能亢进、醛固酮增多症、高催乳素血症、生长激素过多和缺乏对止血参数以及动脉和静脉血栓形成事件的影响的证据。所有这些内分泌疾病都可能对内凝或血栓形成事件的风险有影响。需要进一步的研究来确定这些关联的临床意义。
