Lopez Laureen M, Steiner Markus, Grimes David A, Hilgenberg Deborah, Schulz Kenneth F
Clinical Sciences, FHI 360, Research Triangle Park, North Carolina, USA.
Cochrane Database Syst Rev. 2013 Apr 30;2013(4):CD006964. doi: 10.1002/14651858.CD006964.pub3.
Knowledge of contraceptive effectiveness is crucial to making an informed choice. The consumer has to comprehend the pros and cons of the contraceptive methods being considered. Choice may be influenced by understanding the likelihood of pregnancy with each method and factors that influence effectiveness.
To review all randomized controlled trials comparing strategies for communicating to consumers the effectiveness of contraceptives in preventing pregnancy.
Through February 2013, we searched the computerized databases of MEDLINE, POPLINE, CENTRAL, PsycINFO and CINAHL, ClinicalTrials.gov, and ICTRP. Previous searches also included EMBASE. We also examined references lists of relevant articles. For the initial review, we wrote to known investigators for information about other published or unpublished trials.
We included randomized controlled trials that compared methods for communicating contraceptive effectiveness to consumers. The comparison could be usual practice or an alternative to the experimental intervention.Outcome measures were knowledge of contraceptive effectiveness, attitude about contraception or toward any particular contraceptive, and choice or use of contraceptive method.
For the initial review, two authors independently extracted the data. One author entered the data into RevMan, and a second author verified accuracy. For the update, an author and a research associate extracted, entered, and checked the data.For dichotomous variables, we calculated the Mantel-Haenszel odds ratio with 95% confidence intervals (CI). For continuous variables, we computed the mean difference (MD) with 95% CI.
Seven trials met the inclusion criteria and had a total of 4526 women. Five were multi-site studies. Four trials were conducted in the USA, while Nigeria and Zambia were represented by one study each, and one trial was done in both Jamaica and India.Two trials provided multiple sessions for participants. In one study that examined contraceptive choice, women in the expanded program were more likely to choose sterilization (OR 4.26; 95% CI 2.46 to 7.37) or use a modern contraceptive method (OR 2.35; 95% CI 1.82 to 3.03), i.e., sterilization, pills, injectable, intrauterine device or barrier method. For the other study, the groups received educational interventions with differing format and intensity. Both groups reportedly had increases in contraceptive use, but they did not differ significantly by six months in consistent use of an effective contraceptive, i.e., sterilization, IUD, injectable, implant, and consistent use of oral contraceptives, diaphragm, or male condoms.Five trials provided one session and focused on testing educational material or media. In one study, knowledge gain favored a slide-and-sound presentation versus a physician's oral presentation (MD -19.00; 95% CI -27.52 to -10.48). In another trial, a table with contraceptive effectiveness categories led to more correct answers than a table based on pregnancy numbers [ORs were 2.42 (95% CI 1.43 to 4.12) and 2.19 (95% CI 1.21 to 3.97)] or a table with effectiveness categories and pregnancy numbers [ORs were 2.58 (95% CI 1.5 to 4.42) and 2.03 (95% CI 1.13 to 3.64)]. Still another trial provided structured counseling with a flipchart on contraceptive methods. The intervention and usual-care groups did not differ significantly in choice of contraceptive method (by effectiveness category) or in continuation of the chosen method at three months. Lastly, a study with couples used videos to communicate contraceptive information (control, motivational, contraceptive methods, and both motivational and methods videos). The analyses showed no significant difference between the groups in the types of contraceptives chosen.
AUTHORS' CONCLUSIONS: These trials varied greatly in the types of participants and interventions to communicate contraceptive effectiveness. Therefore, we cannot say overall what would help consumers choose an appropriate contraceptive method. For presenting pregnancy risk data, one trial showed that effectiveness categories were better than pregnancy numbers. In another trial, audiovisual aids worked better than the usual oral presentation. Strategies should be tested in clinical settings and measured for their effect on contraceptive choice. More detailed reporting of intervention content would help in interpreting results. Reports could also include whether the instruments used to assess knowledge or attitudes were tested for validity or reliability. Follow-up should be incorporated to assess retention of knowledge over time. The overall quality of evidence was considered to be low for this review, given that five of the seven studies provided low or very low quality evidence.
了解避孕效果对于做出明智的选择至关重要。消费者必须理解所考虑的避孕方法的优缺点。选择可能会受到对每种方法怀孕可能性以及影响效果的因素的理解的影响。
回顾所有比较向消费者传达避孕方法预防怀孕效果的策略的随机对照试验。
截至2013年2月,我们检索了MEDLINE、POPLINE、CENTRAL、PsycINFO和CINAHL的计算机数据库、ClinicalTrials.gov和ICTRP。以前的检索还包括EMBASE。我们还检查了相关文章的参考文献列表。对于初步综述,我们写信给知名研究者以获取其他已发表或未发表试验的信息。
我们纳入了比较向消费者传达避孕效果方法的随机对照试验。比较可以是常规做法或实验性干预的替代方法。结局指标是对避孕效果的了解、对避孕或任何特定避孕方法的态度,以及避孕方法的选择或使用。
对于初步综述,两位作者独立提取数据。一位作者将数据录入RevMan,另一位作者核实准确性。对于更新内容,一位作者和一名研究助理提取、录入并检查数据。对于二分变量,我们计算了带有95%置信区间(CI)的Mantel-Haenszel优势比。对于连续变量,我们计算了带有95%CI的平均差(MD)。
七项试验符合纳入标准,共有4526名女性。五项是多中心研究。四项试验在美国进行,尼日利亚和赞比亚各有一项研究,一项试验在牙买加和印度均有开展。两项试验为参与者提供了多场培训。在一项研究避孕选择的试验中,参与扩展项目的女性更有可能选择绝育(优势比4.26;95%CI 2.46至7.37)或使用现代避孕方法(优势比2.35;95%CI 1.82至3.03),即绝育、避孕药、注射剂、宫内节育器或屏障法。在另一项试验中,各小组接受了形式和强度不同的教育干预。据报道,两组的避孕措施使用情况均有所增加,但在有效避孕措施(即绝育、宫内节育器、注射剂、植入剂)的持续使用以及口服避孕药、隔膜或男用避孕套的持续使用方面,六个月时两组之间没有显著差异。五项试验提供了一场培训,重点是测试教育材料或媒体。在一项研究中,与医生的口头讲解相比,幻灯片和声音演示在知识获取方面更具优势(平均差 -19.00;95%CI -27.52至 -10.48)。在另一项试验中,与基于怀孕次数的表格相比,带有避孕效果类别的表格能得出更多正确答案[优势比分别为2.42(95%CI 1.43至4.12)和2.19(95%CI 1.21至3.97)],或者与带有效果类别和怀孕次数的表格相比也是如此[优势比分别为2.58(95%CI 1.5至4.42)和2.03(95%CI 1.13至3.64)]。还有一项试验提供了关于避孕方法的结构式咨询,并配有活动挂图。干预组和常规护理组在避孕方法选择(按效果类别)或三个月时所选方法的持续使用方面没有显著差异。最后,一项针对夫妻的研究使用视频来传达避孕信息(对照组、激励性视频、避孕方法视频以及激励性和方法视频)。分析表明,两组在所选避孕方法类型上没有显著差异。
这些试验在参与者类型和传达避孕效果的干预措施方面差异很大。因此,我们无法总体上说什么会帮助消费者选择合适的避孕方法。对于呈现怀孕风险数据,一项试验表明效果类别比怀孕次数更好。在另一项试验中,视听辅助工具比通常的口头讲解效果更好。应在临床环境中对策略进行测试,并衡量其对避孕选择的影响。对干预内容进行更详细的报告将有助于解释结果。报告还可以包括用于评估知识或态度的工具是否经过有效性或可靠性测试。应纳入随访以评估知识随时间的保留情况。鉴于七项研究中有五项提供了低质量或极低质量的证据,本综述的总体证据质量被认为较低。