Neya T, Yamasato T, Mizutani M, Nakayama S
Department of Physiology, Okayama University Medical School, Japan.
Acta Med Okayama. 1990 Apr;44(2):113-5. doi: 10.18926/AMO/30443.
Effects of stimulation of the vagus and sympathetic nerves on bile duct peristalses were studied in pigeons anesthetized with urethane. Vagus stimulation increased the frequency of peristalses. Atropine, hexamethonium and tetrodotoxin abolished this excitatory effect. After atropine, inhibition of peristalses sensitive to tetrodotoxin was produced. Stimulation of sympathetic area in the spinal cord inhibited peristalses. Propranolol converted this effect into an excitatory one, which was abolished by phentolamine. The results suggest that vagal and sympathetic innervations of the bile duct in pigeons are similar to those of the sphincter of Oddi in mammalian species.
在用氨基甲酸乙酯麻醉的鸽子身上，研究了刺激迷走神经和交感神经对胆管蠕动的影响。刺激迷走神经会增加蠕动频率。阿托品、六甲铵和河豚毒素可消除这种兴奋作用。使用阿托品后，会产生对河豚毒素敏感的蠕动抑制。刺激脊髓中的交感神经区域会抑制蠕动。普萘洛尔将这种作用转变为兴奋作用，而酚妥拉明可消除这种兴奋作用。结果表明，鸽子胆管的迷走神经和交感神经支配与哺乳动物物种的Oddi括约肌的支配相似。
