Tateya K
Nihon Heikatsukin Gakkai Zasshi. 1979 Nov;15(3):295-308. doi: 10.1540/jsmr1965.15.295.
The motility of the bile ducts of the pigeon and the effects of autonomic drugs on it were studied in vivo and in vitro. Peristalses which originated rhythmically at the hepatic end of the duct propagated to the duodenal end and excreted the bile into it. Antiperistalses did not occur in vivo. The intervals of peristalses of the duct in vivo changed variably while those of the spontaneous contractions in the isolated duct were fairly constant. No synchronization between the electrical activities recorded at the duodenal end of the duct and the duodenum close to the duct was observed. Cholinergic drugs increased motilities of the duct and duodenum. Adrenaline, noradrenaline and phenylephrine induced the excitation of the duct and isoprenaline slight inhibition. All of these sympathomimetic drugs inhibited duodenal motility. The excitatory effect was abolished by alpha-adrenergic blocking agent, and the inhibitory one was abolished by alpha- and/or beta- adrenergic blocking agents. These results suggest that the bile duct is functionally independent of the duodenum and responsibility of the adrenergic drugs are different between two organs.
对鸽子胆管的运动性及其在体内和体外受自主神经药物的影响进行了研究。在胆管肝端有节律地产生的蠕动波向十二指肠端传播，并将胆汁排入十二指肠。在体内未出现逆蠕动。体内胆管蠕动的间隔变化不定，而离体胆管自发收缩的间隔则相当恒定。未观察到在胆管十二指肠端记录的电活动与靠近胆管的十二指肠之间的同步现象。胆碱能药物增加胆管和十二指肠的运动性。肾上腺素、去甲肾上腺素和去氧肾上腺素可引起胆管兴奋，而异丙肾上腺素则有轻微抑制作用。所有这些拟交感神经药物均抑制十二指肠运动。α-肾上腺素能阻断剂可消除兴奋作用，α-和/或β-肾上腺素能阻断剂可消除抑制作用。这些结果表明，胆管在功能上独立于十二指肠，且肾上腺素能药物在这两个器官中的作用不同。
