Klinck Mary P, Frank Diane, Guillot Martin, Troncy Eric
Groupe de Recherche en Pharmacologie Animale du Québec (GREPAQ), Department of Veterinary Biomedical Sciences, and the Companion Animal Research Group, Department of Clinical Sciences, Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, Quebec J2S 7C6.
Can Vet J. 2012 Nov;53(11):1181-6.
Veterinarians contacted to identify cats diagnosed with osteoarthritis (OA) provided information on signalment, method of diagnosis, treatment and concurrent disease. Owners of 50 cats were interviewed to collect information on specific OA signs observed in the home, relating to mobility, self-maintenance, social and exploratory behavior, and activity and habits at diagnosis and after treatment. Mean age at diagnosis was 12 y; concurrent diseases were common (44%). Owner-reported abnormalities led to OA diagnosis in most cases; either as the primary finding (30%), or combined with abnormal physical examination or radiographic findings (64%). Owners frequently reported changes in mobility, particularly gait, jumping, and use of stairs. Oral or injectable disease-modifying osteoarthritis drugs were the most common treatments (71%). Feline OA diagnosis and therapeutic monitoring appear to rely heavily on owner-perceived signs; physical examination abnormalities may not be detected. Questioning of owners revealed various observable signs potentially useful in OA detection and monitoring.
为确定诊断为骨关节炎(OA)的猫,研究人员联系了兽医,获取了有关猫的特征、诊断方法、治疗情况及并发疾病的信息。研究人员对50只猫的主人进行了访谈,收集了在家中观察到的与活动能力、自我护理、社交和探索行为以及诊断时和治疗后的活动及习惯相关的特定OA体征信息。诊断时的平均年龄为12岁;并发疾病很常见(44%)。在大多数情况下,主人报告的异常表现导致了OA的诊断;要么作为主要发现(30%),要么与体格检查异常或影像学检查结果相结合(64%)。主人经常报告活动能力的变化,尤其是步态、跳跃和上下楼梯的情况。口服或注射用改善病情的骨关节炎药物是最常见的治疗方法(71%)。猫OA的诊断和治疗监测似乎严重依赖于主人察觉到的体征;体格检查异常可能无法被检测到。对主人的询问揭示了各种可能对OA检测和监测有用的可观察体征。