Urs Aadithya B, Augustine Jeyaseelan, Kumar Priya, Arora Shelly, Aggarwal Neha, Sultana Neha
Department of Oral and Maxillofacial Pathology, Maulana Azad Institute of Dental Sciences, New Delhi, India.
J Nat Sci Biol Med. 2013 Jan;4(1):252-7. doi: 10.4103/0976-9668.107320.
Infiltrating lipomatosis of the face is a very rare entity which is characterized by the collection of non-encapsulated mature adipocytes infiltrating local tissues, resulting in craniofacial deformities. Psychomotor development of the patients is normal, esthetics often being the primary concern to seek treatment. The presentation is always unilateral with hypertrophy of hard and soft structures on the affected side of the face. The pathogenesis of the condition is unclear. This condition shows a wide phenotypic range, uncertain prognosis with high rates of recurrence after surgery, and variable post-op cosmetic improvement. The condition shows no gender predilection, with most of the cases presenting in and beyond the second decade of life. Here, we present a series of four cases presenting in varying age groups with history of recurrence in three cases.
面部浸润性脂肪瘤病是一种非常罕见的疾病，其特征是未被包裹的成熟脂肪细胞聚集并浸润局部组织，导致颅面畸形。患者的精神运动发育正常，美观问题往往是寻求治疗的主要原因。该病总是单侧发病，患侧面部的软硬结构均有肥大。其发病机制尚不清楚。这种疾病表现出广泛的表型范围，预后不确定，手术后复发率高，术后美容改善效果不一。该病无性别倾向，大多数病例出现在20岁及以后。在此，我们报告一系列4例不同年龄组的病例，其中3例有复发史。
