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2
Mepivacaine-induced anaphylactic shock in a pregnant woman undergoing combined spinal and epidural anesthesia for cesarean delivery: a case report.剖宫产术联合脊麻-硬膜外麻醉时，甲哌卡因致一名孕妇发生过敏性休克：病例报告
JA Clin Rep. 2019 Dec 19;5(1):84. doi: 10.1186/s40981-019-0302-6.
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General Anesthesia-Related Neurotoxicity in the Developing Brain and Current Knowledge and Practice of Physicians at Guilan Academic Hospitals.发育中大脑的全身麻醉相关神经毒性以及吉兰学术医院医生的当前知识与实践
Anesth Pain Med. 2019 Aug 7;9(4):e92366. doi: 10.5812/aapm.92366. eCollection 2019 Aug.
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Anaphylaxis in Pregnancy in the United States: Risk Factors and Temporal Trends Using National Routinely Collected Data.美国妊娠期过敏反应：使用全国常规收集数据的危险因素和时间趋势。
J Allergy Clin Immunol Pract. 2019 Nov-Dec;7(8):2606-2612.e3. doi: 10.1016/j.jaip.2019.04.047. Epub 2019 May 16.
5
Maternal anaphylactic shock in pregnancy: A case report.孕期母体过敏性休克：一例报告
Medicine (Baltimore). 2018 Sep;97(37):e12351. doi: 10.1097/MD.0000000000012351.
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Anaesthesia, surgery, and life-threatening allergic reactions: epidemiology and clinical features of perioperative anaphylaxis in the 6th National Audit Project (NAP6).麻醉、手术和危及生命的过敏反应：第 6 次国家审计项目（NAP6）中围手术期过敏反应的流行病学和临床特征。
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J Anesth. 2017 Feb;31(1):148-151. doi: 10.1007/s00540-016-2280-4. Epub 2016 Nov 16.
8
Intraoperative anaphylaxis to ranitidine during cesarean section.剖宫产术中雷尼替丁引起的过敏反应
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Spinal pethidine for elective caesarean section.
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10
Histamine-releasing and allergenic properties of opioid analgesic drugs: resolving the two.阿片类镇痛药的组胺释放特性与变应原特性：对二者的解析
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剖宫产术中哌替啶诱发过敏反应疑似病例的成功处理

Successful Management of a Suspected Case of Meperidine-Induced Anaphylaxis in Cesarean Delivery.

作者信息

Biazar Gelareh, Farzi Farnoush, Chaibakhsh Yasmin, Habibi Mohammad Reza, Khosousi Sani Mahsa, Mirmansouri Ladan

机构信息

Anesthesiology Research Center, Department of Anesthesiology, Alzahra Hospital, Guilan University of Medical Sciences, Rasht, Iran.

Reproductive Health Research Center, Department of Obstetrics and Gynecology, Al-Zahra Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.

出版信息

Anesth Pain Med. 2020 Aug 31;10(5):e104796. doi: 10.5812/aapm.104796. eCollection 2020 Oct.

DOI:10.5812/aapm.104796
PMID:34150563
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8207837/
Abstract

INTRODUCTION

Meperidine is known as the gold standard drug for shivering after spinal anesthesia (SA). This drug has been used widely and safely during the Cesarean Section (CS).

CASE PRESENTATION

This case report presents an anaphylaxis reaction to a single intravenous dose of 25 mg meperidine, aiming to control shivering during CS under SA a few minutes after surgical incision.

CONCLUSIONS

The condition was well managed with timely intervention. This rare fetal reaction to meperidine is worthy of reporting to make the medical team aware of the potential risks of anaphylaxis due to many routine safe drugs.

摘要

引言

哌替啶是脊髓麻醉（SA）后寒战的金标准药物。该药物在剖宫产（CS）过程中已被广泛且安全地使用。

病例报告

本病例报告呈现了对单次静脉注射25毫克哌替啶的过敏反应，旨在控制SA下CS手术切口后几分钟内的寒战。

结论

通过及时干预，病情得到了妥善处理。这种哌替啶罕见的胎儿反应值得报告，以使医疗团队意识到许多常规安全药物可能引发过敏反应的潜在风险。