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成人匐行性水疱性淋巴瘤 1 例并文献复习

Hydroa vacciniforme-like lymphoma of an adult: a case report with review of the literature.

机构信息

Department of Dermatovenerology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan, China.

出版信息

Diagn Pathol. 2013 May 1;8:72. doi: 10.1186/1746-1596-8-72.

Abstract

UNLABELLED

Hydroa vacciniforme-like lymphoma (HVL) is a rare type of Epstein-Barr virus (EBV)-positive lymphoma of cytotoxic T-cell or natural killer cell origin that mainly affect children, characterized by a vesicopapular skin eruption that clinically resemble hydroa vacciniforme (HV). In current study, we report an adult patient with the tumor. The patient presented similar morphologic, immunophenotypic and genotypic changes of the disease with that occurred in children, whereas clinically, he showed a prolonged clinical course without hepatosplenomegaly or generalized lymphadenopathy. Whether there are some differences in biologic behavior between children and adults still remains unknown and it is necessary to collect more data to observe and to investigate in the future.

VIRTUAL SLIDES

The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/7644172219178472.

摘要

未注明

类痘病毒样淋巴瘤(HVL)是一种罕见的 EBV 阳性淋巴瘤,起源于细胞毒性 T 细胞或自然杀伤细胞,主要影响儿童,其特征为水疱性丘疹性皮疹,临床上类似于水痘(HV)。在本研究中,我们报告了一例成人患者的肿瘤。该患者表现出与儿童相似的形态、免疫表型和基因型改变,但临床表现为病程延长,无肝脾肿大或全身淋巴结病。儿童和成人之间的生物学行为是否存在差异尚不清楚,未来有必要收集更多数据进行观察和研究。

虚拟幻灯片

本文的虚拟幻灯片可在此处找到:http://www.diagnosticpathology.diagnomx.eu/vs/7644172219178472。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08fd/3662161/9e544faa1e56/1746-1596-8-72-1.jpg

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