Markaki S, Prevedorou D, Kyratsis G, Bouropoulou V
Department of Pathology, Athènes, Greece.
Arch Anat Cytol Pathol. 1990;38(3):114-6.
An unusual case of a microfollicular adenoma of the thyroid gland with signet-ring cells in a 36-year-old euthyroid man is described. Mucin stains demonstrated the presence of mainly neutral glycoproteins with focal participation of acidic groups. Immunohistochemical staining for thyroglobulin was strongly positive. The apparent "mucin secretion" described in these rare neoplasms could be due to the histochemical staining of carbohydrate components or breakdown products of thyroglobulin and colloid. The published work on primary mucin secreting tumors of the thyroid gland is reviewed.
本文描述了一例罕见的甲状腺微滤泡性腺瘤，患者为一名36岁甲状腺功能正常的男性，肿瘤内可见印戒细胞。黏液染色显示主要存在中性糖蛋白，酸性基团有局灶性参与。甲状腺球蛋白免疫组化染色呈强阳性。这些罕见肿瘤中所描述的明显“黏液分泌”可能是由于甲状腺球蛋白和胶体的碳水化合物成分或分解产物的组织化学染色所致。本文对已发表的关于甲状腺原发性黏液分泌性肿瘤的研究进行了综述。
