[一名白血病患儿的迟发性麻疹脑炎]
[Delayed measles encephalitis in a leukemic child].
作者信息
Monfort-Gouraud M, Robain O, Boccara F, Badoual J
机构信息
Service de Pédiatrie B, Hôpital Saint-Vincent-de-Paul, Paris.
出版信息
Arch Fr Pediatr. 1990 Apr;47(4):275-7.
A case of measles encephalitis of the delayed type in a 5 year-old girl is reported. The encephalitis occurred 6 months after a measles which supervened just after the 18th monthly reinduction treatment for acute lymphoblastic leukemia. The child died one month later. This measles inclusion body encephalitis (MIBE) was confirmed by the presence of intracellular inclusions in the brain cells visualized by electron microscopy. The evidence of viral related intracellular nucleocapsides was confirmed by in situ hybridization. These nucleocapsides were identical to those seen in subacute sclerosing panencephalitis.
报告了一例5岁女孩的迟发型麻疹脑炎病例。该脑炎发生在急性淋巴细胞白血病第18次每月再诱导治疗后不久出现的麻疹6个月后。患儿1个月后死亡。通过电子显微镜观察到脑细胞内存在包涵体，证实为麻疹包涵体脑炎（MIBE）。原位杂交证实了病毒相关细胞内核衣壳的存在。这些核衣壳与亚急性硬化性全脑炎中所见的核衣壳相同。
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