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Targeting tumors using nanoparticle platforms: a phase I study of a systemically administered gene therapy system.

作者信息

Larson Christopher, Mendez Natalie, Reid Tony

机构信息

Division of Hematology-Oncology, Department of Medicine, University of California, San Diego, La Jolla, California 92093, USA.

出版信息

Mol Ther. 2013 May;21(5):922-3. doi: 10.1038/mt.2013.76.

DOI:10.1038/mt.2013.76
PMID:23636291
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3666643/
Abstract
摘要

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本文引用的文献

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Phase I study of a systemically delivered p53 nanoparticle in advanced solid tumors.一项在晚期实体瘤中系统递送达 p53 纳米颗粒的 I 期研究。
Mol Ther. 2013 May;21(5):1096-103. doi: 10.1038/mt.2013.32. Epub 2013 Apr 23.
2
In vivo gene delivery by nonviral vectors: overcoming hurdles?非病毒载体体内基因递送:克服障碍?
Mol Ther. 2012 Jul;20(7):1298-304. doi: 10.1038/mt.2012.79. Epub 2012 Apr 24.
3
Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans.静脉注射多机制癌症靶向溶瘤痘病毒在人体中的应用。
Nature. 2011 Aug 31;477(7362):99-102. doi: 10.1038/nature10358.
4
Clinical outcomes and correlates of TP53 mutations and cancer.TP53 基因突变与癌症的临床结局和相关性。
Cold Spring Harb Perspect Biol. 2010 Mar;2(3):a001016. doi: 10.1101/cshperspect.a001016.
5
The transferrin receptor part I: Biology and targeting with cytotoxic antibodies for the treatment of cancer.转铁蛋白受体第一部分:生物学特性及用细胞毒性抗体靶向治疗癌症
Clin Immunol. 2006 Nov;121(2):144-58. doi: 10.1016/j.clim.2006.06.010. Epub 2006 Aug 10.
6
Is there a role for routine p53 testing in colorectal cancer?
J Clin Oncol. 2005 Oct 20;23(30):7395-6. doi: 10.1200/JCO.2005.07.021. Epub 2005 Sep 26.
7
P53 abnormalities and outcomes in colorectal cancer: a systematic review.结直肠癌中P53异常与预后:一项系统评价
Br J Cancer. 2005 Feb 14;92(3):434-44. doi: 10.1038/sj.bjc.6602358.
8
Enhanced transfection efficiency of a systemically delivered tumor-targeting immunolipoplex by inclusion of a pH-sensitive histidylated oligolysine peptide.通过包含对pH敏感的组氨酸化寡聚赖氨酸肽提高全身递送的肿瘤靶向免疫脂质体复合物的转染效率。
Nucleic Acids Res. 2004 Mar 16;32(5):e48. doi: 10.1093/nar/gnh049.
9
Systemic tumor-targeted gene delivery by anti-transferrin receptor scFv-immunoliposomes.通过抗转铁蛋白受体单链抗体片段免疫脂质体进行全身肿瘤靶向基因递送。
Mol Cancer Ther. 2002 Mar;1(5):337-46.
10
In vivo characteristics of cationic liposomes as delivery vectors for gene therapy.阳离子脂质体作为基因治疗递送载体的体内特性
Pharm Res. 2002 Nov;19(11):1599-605. doi: 10.1023/a:1020989709019.