通过α-氨基[1-¹⁴C]异丁酸在组织中的蓄积表明，饥饿和再喂食时泌乳大鼠乳腺和肝脏中氨基酸代谢的相互变化。
Reciprocal changes in amino acid metabolism in mammary gland and liver of the lactating rat on starvation and refeeding as indicated by the tissue accumulation of alpha-amino[1-14C]isobutyrate.
作者信息
Tedstone A E, Ilic V, Williamson D H
机构信息
Nuffield Department of Clinical Medicine, Radcliffe Infirmary, Oxford, U.K.
出版信息
Biochem J. 1990 Jun 15;268(3):799-802. doi: 10.1042/bj2680799.
Abstract
Measurements of the tissue accumulation in vivo and in vitro by hepatocytes and mammary-gland acini of alpha-amino[1-14C]isobutyrate ([1-14C]AIB) were compared in virgin and lactating rats. The results indicate the existence of a reciprocal relationship between mammary gland and liver for AIB accumulation that is dependent on the lactational and the nutritional state of the rat. This suggests that amino acids are preferentially directed to the mammary gland during active lactation.
摘要
比较了初产和泌乳大鼠体内和体外肝细胞及乳腺腺泡对α-氨基[1-¹⁴C]异丁酸（[1-¹⁴C]AIB）的组织蓄积情况。结果表明，大鼠乳腺和肝脏对AIB的蓄积存在相互关系，这种关系取决于大鼠的泌乳和营养状态。这表明在活跃泌乳期间，氨基酸优先导向乳腺。
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