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脊柱手术后心脏并发症的危险因素。

Risk factors for cardiac complications after spine surgery.

作者信息

Guyot Juan P, Cizik Amy, Bransford Richard, Bellabarba Carlo, Lee Michael J

机构信息

Harborview Medical Center, Department of Orthopedics and Sports Medicine, Seattle, Washington, USA.

出版信息

Evid Based Spine Care J. 2010 Aug;1(2):18-25. doi: 10.1055/s-0028-1100910.

Abstract

STUDY DESIGN

Registry study using prospectively collected data Objective:  To determine risk factors for cardiac complications in spine surgery.

METHODS

The Spine End RESULTS Registry 2003-2004 is an exhaustive database of 1,592 patients who underwent spine surgery at the University of Washington Medical Center or Harborview Medical Center. Detailed information regarding patient demographic, medical comorbidity, surgical invasiveness and adverse outcomes were prospectively recorded. The primary outcome of measure was the occurrence of a cardiac complication in the perioperative period. Relative risk (RR) and 95% confidence intervals were calculated for each of the categorical variables. Multiple log-binomial regression analysis was performed to investigate the independent factors associated with cardiac complication.

RESULTS

The incidence of cardiac complication after spine surgery was 6.7%. There were 136 cardiac complications in 107 patients after spine surgery. Age, diabetes, previous cardiac history, elevated adjusted Charlson comorbidity score, revision surgery, combined anterior-posterior approaches, and surgical invasiveness were statistically significant risk factors for cardiac complication after spine surgery.

CONCLUSIONS

The results of the present study suggest numerous statistically significant risk factors for cardiac complications after spine surgery. These results may aid the clinician with preoperative risk stratification and patient counseling. [Table: see text] The definiton of the different classes of evidence is available on page 73.

摘要

研究设计

采用前瞻性收集数据的登记研究

目的

确定脊柱手术中心脏并发症的危险因素。

方法

“脊柱最终结果登记处2003 - 2004”是一个详尽的数据库,涵盖了在华盛顿大学医学中心或海港景医疗中心接受脊柱手术的1592例患者。前瞻性记录了有关患者人口统计学、医疗合并症、手术侵袭性和不良结局的详细信息。测量的主要结局是围手术期心脏并发症的发生情况。计算每个分类变量的相对风险(RR)和95%置信区间。进行多对数二项回归分析以研究与心脏并发症相关的独立因素。

结果

脊柱手术后心脏并发症的发生率为6.7%。脊柱手术后107例患者发生了136次心脏并发症。年龄、糖尿病、既往心脏病史、调整后的Charlson合并症评分升高、翻修手术、前后联合入路以及手术侵袭性是脊柱手术后心脏并发症的统计学显著危险因素。

结论

本研究结果表明脊柱手术后心脏并发症存在众多统计学显著的危险因素。这些结果可能有助于临床医生进行术前风险分层和患者咨询。[表格:见正文]不同证据类别的定义见第73页。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b875/3623101/2110a24e06f6/ebsj01018-1.jpg

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