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脊柱手术后肺部并发症的危险因素。

Risk factors for pulmonary complications after spine surgery.

作者信息

Imposti Felix, Cizik Amy, Bransford Richard, Bellabarba Carlo, Lee Michael J

机构信息

Harborview Medical Center, Department of Orthopedics and Sports Medicine, Seattle, Washington, USA.

出版信息

Evid Based Spine Care J. 2010 Aug;1(2):26-33. doi: 10.1055/s-0028-1100911.

Abstract

STUDY DESIGN

Registry study with prospectively collected data Objective:  To determine risk factors for pulmonary complications in spine surgery.

METHODS

The Spine End RESULTS Registry 2003-2004 is an exhaustive database of 1,592 patients who underwent spine surgery at the University of Washington Medical Center or Harborview Medical Center. Detailed information regarding patient demographic, medical comorbidity, and comorbidities, surgical invasiveness and adverse outcomes were prospectively recorded. The primary outcome measure was the occurrence of a pulmonary complication following surgery. Univariate relative risks and 95% confidence intervals for each of the risk factors were determined. Multivariate log binomial regression analysis was performed to investigate the association between each risk factor and a pulmonary complication, while controlling for other important risk factors.

RESULTS

Altogether, there were 199 pulmonary complications after spine surgery. The cumulative incidence of a respiratory complication after spine surgery was 9% (144 patients). Multivariate analysis suggested gender, chronic obstructive pulmonary disease, congestive heart failure, diabetes, age, diagnosis, surgical invasiveness and surgery in the thoracic spine are significant risk factors for pulmonary complications after spinal surgery.

CONCLUSIONS

The results of the present study suggest numerous statistically significant risk factors for pulmonary complications after spine surgery. These results may aid the clinician with preoperative risk stratification and patient counseling. [Table: see text] The definiton of the different classes of evidence is available on page 73.

摘要

研究设计

采用前瞻性收集数据的登记研究

目的

确定脊柱手术肺部并发症的危险因素。

方法

脊柱终末期结果登记库2003 - 2004年的数据来自华盛顿大学医学中心或海港景医疗中心接受脊柱手术的1592例患者,是一个详尽的数据库。前瞻性记录了患者人口统计学、医疗合并症、手术侵袭性及不良结局的详细信息。主要结局指标为术后肺部并发症的发生情况。确定每个危险因素的单变量相对风险及95%置信区间。进行多变量对数二项回归分析,以研究每个危险因素与肺部并发症之间的关联,同时控制其他重要危险因素。

结果

脊柱手术后共有199例肺部并发症。脊柱手术后呼吸并发症的累积发生率为9%(144例患者)。多变量分析表明,性别、慢性阻塞性肺疾病、充血性心力衰竭、糖尿病、年龄、诊断、手术侵袭性及胸椎手术是脊柱手术后肺部并发症的重要危险因素。

结论

本研究结果提示脊柱手术后肺部并发症存在众多具有统计学意义的危险因素。这些结果可能有助于临床医生进行术前风险分层及患者咨询。[表:见正文]不同证据等级的定义见第73页。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc04/3623103/a964c121420d/ebsj01026-1.jpg

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