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复杂小儿及成人脊柱畸形术后肺部并发症:对西非某单一治疗中心连续治疗患者的回顾性研究

Postoperative Pulmonary Complications in Complex Pediatric and Adult Spine Deformity: A Retrospective Review of Consecutive Patients Treated at a Single Site in West Africa.

作者信息

Wulff Irene, Duah Henry Ofori, Osei Tutu Henry, Ofori-Amankwah Gerhard, Yankey Kwadwo Poku, Owiredu Mabel Adobea, Bidemi Yahaya Halima, Akoto Harry, Oteng-Yeboah Audrey, Boachie-Adjei Oheneba

机构信息

FOCOS Orthopaedic Hospital, Accra, Ghana.

出版信息

Global Spine J. 2021 Oct;11(8):1208-1214. doi: 10.1177/2192568220942482. Epub 2020 Aug 10.

Abstract

STUDY DESIGN

Retrospective review of consecutive series.

OBJECTIVES

This study sought to assess the incidence, risk factors, and outcomes of pulmonary complication following complex spine deformity surgery in a low-resourced setting in West Africa.

METHODS

Data of 276 complex spine deformity patients aged 3 to 25 years who were treated consecutively was retrospectively reviewed. Patients were categorized into 2 groups during data analysis based on pulmonary complication status: group 1: yes versus group 2: no. Comparative descriptive and inferential analysis were performed to compare the 2 groups.

RESULTS

The incidence of pulmonary complication was 17/276 (6.1%) in group 1. A total of 259 patients had no events (group 2). There were 8 males and 9 females in group 1 versus 100 males and 159 females in group 2. Body mass index was similar in both groups (17.2 vs 18.4 kg/m, = .15). Average values (group 1 vs group 2, respectively) were as follows: preoperative sagittal Cobb angle (90.6° vs 88.7°, = .87.), coronal Cobb angle (95° vs 88.5°, = .43), preoperative forced vital capacity (45.3% vs 62.0%, = .02), preoperative FEV (forced expiratory volume in 1 second) (41.9% vs 63.1%, < .001). Estimated blood loss, operating room time, and surgery levels were similar in both groups. Thoracoplasty and spinal osteotomies were performed at similar rates in both groups, except for Smith-Peterson osteotomy. Multivariate logistic regression showed that every unit increase in preoperative FEV (%) decreases the odds of pulmonary complication by 9% (OR = 0.91, 95% CI 0.84-0.98, = .013).

CONCLUSION

The observed 6.1% incidence of pulmonary complications is comparable to reported series. Preoperative FEV was an independent predictor of pulmonary complications. The observed case fatality rate following pulmonary complications (17%) highlights the complexity of cases in underserved regions and the need for thorough preoperative evaluation to identify high-risk patients.

摘要

研究设计

对连续病例系列进行回顾性分析。

目的

本研究旨在评估在西非资源匮乏地区进行复杂脊柱畸形手术后肺部并发症的发生率、危险因素及结局。

方法

对276例年龄在3至25岁之间连续接受治疗的复杂脊柱畸形患者的数据进行回顾性分析。在数据分析过程中,根据肺部并发症状况将患者分为两组:第1组:有并发症;第2组:无并发症。进行比较性描述性和推断性分析以比较两组情况。

结果

第1组肺部并发症发生率为17/276(6.1%)。共有259例患者无并发症发生(第2组)。第1组有8例男性和9例女性,第2组有100例男性和159例女性。两组的体重指数相似(17.2 vs 18.4 kg/m²,P = 0.15)。(第1组与第2组的)平均值分别如下:术前矢状面Cobb角(90.6° vs 88.7°,P = 0.87),冠状面Cobb角(95° vs 88.5°,P = 0.43),术前用力肺活量(45.3% vs 62.0%,P = 0.02),术前1秒用力呼气量(FEV)(41.9% vs 63.1%,P < 0.001)。两组的估计失血量、手术时间和手术节段相似。除了Smith-Peterson截骨术外,两组胸廓成形术和脊柱截骨术的实施率相似。多因素逻辑回归分析显示,术前FEV(%)每增加一个单位,肺部并发症的发生几率降低9%(OR = 0.91,95%CI 0.84 - 0.98,P = 0.013)。

结论

观察到的6.1%的肺部并发症发生率与已报道的系列研究相当。术前FEV是肺部并发症的独立预测因素。观察到的肺部并发症后的病死率(17%)凸显了医疗服务不足地区病例的复杂性以及对高危患者进行全面术前评估的必要性。

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本文引用的文献

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