Department of Biotechnology, Quaid-i-Azam University, Islamabad, Pakistan.
PLoS One. 2013 Apr 18;8(4):e61667. doi: 10.1371/journal.pone.0061667. Print 2013.
Astroviruses are globally known enteropathogens causing gastroenteritis and diarrhea, with eight well defined serotypes. Epidemiological studies have recognized serotype-1 as the most common subtype but no such data is available in Pakistan. During 2009-2010, we found astroviruses in 41 out of 535 (7%) samples collected from hospitalized children. Thirty one strains belonged to serotype-1 and clustered into two distinct lineages. Serotype-3, -4 and -6 were detected with 97-98% genetic homology to Indian and Chinese strains.
星状病毒是全球公认的肠道病原体，可引起肠胃炎和腹泻，有 8 种明确的血清型。流行病学研究已确定血清型 1 是最常见的亚型，但在巴基斯坦尚无此类数据。在 2009 年至 2010 年期间，我们从 535 名住院儿童的样本中发现了 41 种星状病毒。31 株属于血清型 1，分为两个不同的谱系。血清型 3、4 和 6与印度和中国的菌株具有 97-98%的遗传同源性。
