Méndez-Toss Martha, Griffin Dixie D, Calva Juan, Contreras Juan F, Puerto Fernando I, Mota Felipe, Guiscafré Héctor, Cedillo Roberto, Muñoz Onofre, Herrera Ismael, López Susana, Arias Carlos F
Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, Mexico.
J Clin Microbiol. 2004 Jan;42(1):151-7. doi: 10.1128/JCM.42.1.151-157.2004.
The prevalence and type diversity of human astroviruses (HAstV) in children with symptomatic and asymptomatic infections were determined in five localities of Mexico. HAstV were detected in 4.6 (24 of 522) and 2.6% (11 of 428) of children with and without diarrhea, respectively. Genotyping of the detected strains showed that at least seven (types 1 to 4 and 6 to 8) of the eight known HAstV types circulated in Mexico between October 1994 and March 1995. HAstV types 1 and 3 were the most prevalent in children with diarrhea, although they were not found in all localities studied. HAstV type 8 was found in Mexico City, Monterrey, and Mérida; in the last it was as prevalent (40%) as type 1 viruses, indicating that this astrovirus type is more common than previously recognized. A correlation between the HAstV infecting type and the presence or absence of diarrheic symptoms was not observed. Enteric adenoviruses were also studied, and they were found to be present in 2.3 (12 of 522) and 1.4% (6 of 428) of symptomatic and asymptomatic children, respectively.
在墨西哥的五个地区，对有症状和无症状感染儿童中人类星状病毒（HAstV）的流行情况和类型多样性进行了测定。在有腹泻和无腹泻的儿童中，HAstV的检出率分别为4.6%（522例中的24例）和2.6%（428例中的11例）。对检测到的毒株进行基因分型显示，在1994年10月至1995年3月期间，墨西哥流行着已知的8种HAstV类型中的至少7种（1至4型以及6至8型）。1型和3型HAstV在腹泻儿童中最为常见，不过并非在所有研究地区都能发现。8型HAstV在墨西哥城、蒙特雷和梅里达被发现；在梅里达，其流行程度（40%）与1型病毒相同，这表明该星状病毒类型比之前认为的更为常见。未观察到HAstV感染类型与腹泻症状的有无之间存在关联。还对肠道腺病毒进行了研究，发现它们分别在2.3%（522例中的12例）有症状儿童和1.4%（428例中的6例）无症状儿童中存在。
