Mysiw W J, Colachis S C, Vetter J
Department of Physical Medicine, Ohio State University, Columbus 43210-1290.
Am J Phys Med Rehabil. 1990 Jun;69(3):112-6. doi: 10.1097/00002060-199006000-00002.
Ulnar and tibial F response parameters were characterized in 17 healthy controls and 26 subjects with type I diabetes mellitus meeting or exceeding criteria for mild diabetic peripheral neuropathy. The presence of mild diabetic peripheral neuropathy was determined by utilizing conventional nerve conduction studies, the neuropathy symptoms score and a neurologic examination. Ulnar and tibial nerve F response latency, amplitude, duration, chronodispersion and persistence were then compared between populations. The relationship between tibial F response persistence and minimal F response latency was assessed in both populations. In addition, the relationship between tibial F response persistence and tibial nerve conduction velocity and tibial nerve compound action potential characteristics (e.g., latency, amplitude and duration) was assessed in the diabetic population. The results indicate that ulnar F response latency and chronodispersion failed to differentiate the subject and control populations; however, significantly decreased ulnar F response amplitude and duration were noted in the diabetic population. In the tibial nerve, the F response persistence was significantly decreased in the diabetic population but persistence did not correlate with compound muscle action potential latency, amplitude, duration or nerve conduction velocity. Finally, the tibial F response latency, amplitude, duration and chronodispersion failed to differentiate the control and diabetic populations.
对17名健康对照者和26名符合或超过轻度糖尿病性周围神经病变标准的I型糖尿病患者的尺神经和胫神经F波反应参数进行了表征。通过使用传统神经传导研究、神经病变症状评分和神经学检查来确定轻度糖尿病性周围神经病变的存在。然后比较了两组人群的尺神经和胫神经F波反应潜伏期、波幅、时限、离散度和出现率。评估了两组人群中胫神经F波反应出现率与最小F波反应潜伏期之间的关系。此外，还评估了糖尿病患者中胫神经F波反应出现率与胫神经传导速度以及胫神经复合动作电位特征（如潜伏期、波幅和时限）之间的关系。结果表明，尺神经F波反应潜伏期和离散度未能区分研究对象和对照组人群；然而，糖尿病患者中尺神经F波反应波幅和时限显著降低。在胫神经方面，糖尿病患者中F波反应出现率显著降低，但出现率与复合肌肉动作电位潜伏期、波幅、时限或神经传导速度无关。最后，胫神经F波反应潜伏期、波幅、时限和离散度未能区分对照组和糖尿病患者人群。
