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[1例经氟桂利嗪治疗后临床症状改善的柔脑膜血管瘤病]

[A case of leptomeningeal angiomatosis clinically improved by flunarizine].

作者信息

Nitta H, Asou S, Iwasaki Y

机构信息

Department of Pediatrics, Japanese Red Cross Medical Center, Tokyo.

出版信息

No To Hattatsu. 1990 May;22(3):279-83.

PMID:2363966
Abstract

A 3-year-old boy was reported, who suffered from attacks of hemiconvulsion and hemiparesis. Carotid angiography showed anomalous cerebral venous drainage with a decrease in the number of superficial cortical veins, and dilatation of medullary veins and deep veins. Brain scanning demonstrated abnormality of regional cerebral blood flow and delay of both uptake and drainage of radionuclide. These are similar to the findings known in Sturge-Weber disease, so that a leptomeningeal angiomatosis was strongly suggested. Flunarizine which has a cerebral vasodilating effect improved his clinical symptoms significantly, and his attack disappeared completely.

摘要

据报道,一名3岁男孩患有半身惊厥和偏瘫发作。颈动脉血管造影显示脑静脉引流异常,浅表皮质静脉数量减少,髓质静脉和深静脉扩张。脑部扫描显示局部脑血流异常,放射性核素摄取和引流延迟。这些与斯特奇-韦伯综合征的已知表现相似,因此强烈提示为软脑膜血管瘤病。具有脑血管舒张作用的氟桂利嗪显著改善了他的临床症状,其发作完全消失。

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