Department of Chemistry, Baghdad-ul-Jadeed Campus, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan.
Phytochemistry. 2013 Sep;93:199-202. doi: 10.1016/j.phytochem.2013.03.018. Epub 2013 May 1.
An antibiotic polyketide, Cryptosporioptide (1) was isolated from the culture extract of the endophytic fungus Cryptosporiopsis sp. The structure of Cryptosporioptide has been established with the help of 1D ((1)H, (13)C), 2D NMR (HSQC, HMBC, COSY, NOESY) techniques and mass spectrometry (FABMS, HRFABMS). The absolute configuration was established by means of electronic circular dichroism (ECD). Cryptosporioptide exhibited both lipoxygenase inhibitory and anti-Bacillus megaterium activities.
一种抗生素聚酮化合物,Cryptosporioptide(1)从内生真菌 Cryptosporiopsis sp 的培养提取物中分离得到。Cryptosporioptide 的结构是通过 1D((1)H、(13)C)、2D NMR(HSQC、HMBC、COSY、NOESY)技术和质谱(FABMS、HRFABMS)确定的。绝对构型是通过电子圆二色性(ECD)确定的。Cryptosporioptide 同时具有脂氧合酶抑制和抗巨大芽孢杆菌活性。