UCL-Institute of Child Health, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Semin Fetal Neonatal Med. 2013 Aug;18(4):192-5. doi: 10.1016/j.siny.2013.04.003. Epub 2013 Apr 30.
It is important to accurately diagnose epileptic seizures in early life to optimise management and prognosis. Conversely, however, many different movements and behaviours may manifest in the neonatal period and infancy that may not have at their root cause a change in electrical activity of the brain. It is important to distinguish them from epileptic seizures to avoid over- and inappropriate treatment. Some are physiological in the normal infant, such as neonatal tremor, benign neonatal sleep myoclonus, and shuddering attacks, whereas others may herald alternative rare neurological diagnoses with differing prognoses such as hyperekplexia, paroxysmal extreme pain disorder and alternating hemiplegia of childhood. Here are highlighted the key clinical features that distinguish some of these disorders, their management and prognosis.
早期准确诊断婴儿癫痫发作对优化管理和预后非常重要。然而，相反地，许多不同的运动和行为可能在新生儿期和婴儿期表现出来，其根本原因不一定是大脑电活动的改变。区分它们与癫痫发作以避免过度和不适当的治疗非常重要。有些是正常婴儿的生理现象，如新生儿震颤、良性新生儿睡眠肌阵挛和颤抖发作，而另一些则可能预示着其他罕见的神经诊断，预后不同，如肌阵挛性张力障碍、阵发性极度疼痛障碍和儿童交替性偏瘫。这里强调了一些区分这些疾病的关键临床特征、它们的治疗和预后。
