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沙特阿拉伯癫痫的人口统计学、临床特征及管理策略:一项系统综述

Demographics, Clinical Characteristics, and Management Strategies of Epilepsy in Saudi Arabia: A Systematic Review.

作者信息

Almuqairsha Samer A, Al-Harbi Faisal A, Alaidah Alwleed M, Al-Mutairi Turki A, Al-Oadah Emad K, Almatham Areen E, Alharbi Fahad M, Almoshaigah Albara N

机构信息

Internal Medicine, Qassim University, Buraydah, SAU.

College of Medicine, Qassim University, Buraydah, SAU.

出版信息

Cureus. 2024 Jun 29;16(6):e63436. doi: 10.7759/cureus.63436. eCollection 2024 Jun.

Abstract

Epilepsy accounts for a large part of the global burden of neurological disorders. This review aimed to assess the demographics, clinical characteristics, and management of patients with epilepsy in Saudi Arabia based on studies published from 2018 to 2023. A systematic review was carried out using PubMed, Medline, Embase, and Cochrane Library from January 2018 to January 2023, where key terms related to the epidemiology, clinical characteristics, treatment, and management strategy of epilepsy in Saudi Arabia were used to search for related studies. All relevant articles published in this period in the English language were included, and data about authors, year of the study, sample size, study design, demographic characteristics, clinical characteristics, and treatment strategy were collected. A male preponderance, a 6-24.9% family history of epilepsy, an equal distribution of focal and tonic-clonic epilepsy, EEG abnormalities of 19.7-70%, and a higher prevalence of monotherapy regimens were the main findings of this review.

摘要

癫痫在全球神经系统疾病负担中占很大一部分。本综述旨在根据2018年至2023年发表的研究,评估沙特阿拉伯癫痫患者的人口统计学、临床特征和管理情况。2018年1月至2023年1月,利用PubMed、Medline、Embase和Cochrane图书馆进行了一项系统综述,使用与沙特阿拉伯癫痫的流行病学、临床特征、治疗和管理策略相关的关键词搜索相关研究。纳入了该时期以英文发表的所有相关文章,并收集了关于作者、研究年份、样本量、研究设计、人口统计学特征、临床特征和治疗策略的数据。本综述的主要发现包括男性占优势、癫痫家族史为6 - 24.9%、局灶性癫痫和强直阵挛性癫痫分布均等、脑电图异常率为19.7 - 70%以及单药治疗方案的患病率较高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abc0/11284618/2ad29806d25e/cureus-0016-00000063436-i01.jpg

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