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沙特阿拉伯癫痫的人口统计学、临床特征及管理策略:一项系统综述

Demographics, Clinical Characteristics, and Management Strategies of Epilepsy in Saudi Arabia: A Systematic Review.

作者信息

Almuqairsha Samer A, Al-Harbi Faisal A, Alaidah Alwleed M, Al-Mutairi Turki A, Al-Oadah Emad K, Almatham Areen E, Alharbi Fahad M, Almoshaigah Albara N

机构信息

Internal Medicine, Qassim University, Buraydah, SAU.

College of Medicine, Qassim University, Buraydah, SAU.

出版信息

Cureus. 2024 Jun 29;16(6):e63436. doi: 10.7759/cureus.63436. eCollection 2024 Jun.

DOI:10.7759/cureus.63436
PMID:39077233
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11284618/
Abstract

Epilepsy accounts for a large part of the global burden of neurological disorders. This review aimed to assess the demographics, clinical characteristics, and management of patients with epilepsy in Saudi Arabia based on studies published from 2018 to 2023. A systematic review was carried out using PubMed, Medline, Embase, and Cochrane Library from January 2018 to January 2023, where key terms related to the epidemiology, clinical characteristics, treatment, and management strategy of epilepsy in Saudi Arabia were used to search for related studies. All relevant articles published in this period in the English language were included, and data about authors, year of the study, sample size, study design, demographic characteristics, clinical characteristics, and treatment strategy were collected. A male preponderance, a 6-24.9% family history of epilepsy, an equal distribution of focal and tonic-clonic epilepsy, EEG abnormalities of 19.7-70%, and a higher prevalence of monotherapy regimens were the main findings of this review.

摘要

癫痫在全球神经系统疾病负担中占很大一部分。本综述旨在根据2018年至2023年发表的研究,评估沙特阿拉伯癫痫患者的人口统计学、临床特征和管理情况。2018年1月至2023年1月,利用PubMed、Medline、Embase和Cochrane图书馆进行了一项系统综述,使用与沙特阿拉伯癫痫的流行病学、临床特征、治疗和管理策略相关的关键词搜索相关研究。纳入了该时期以英文发表的所有相关文章,并收集了关于作者、研究年份、样本量、研究设计、人口统计学特征、临床特征和治疗策略的数据。本综述的主要发现包括男性占优势、癫痫家族史为6 - 24.9%、局灶性癫痫和强直阵挛性癫痫分布均等、脑电图异常率为19.7 - 70%以及单药治疗方案的患病率较高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abc0/11284618/2ad29806d25e/cureus-0016-00000063436-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abc0/11284618/2ad29806d25e/cureus-0016-00000063436-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abc0/11284618/2ad29806d25e/cureus-0016-00000063436-i01.jpg

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本文引用的文献

1
Social Anxiety, Social Support, and Quality of Life in Patients With Epilepsy at a Tertiary Care Hospital in Saudi Arabia.沙特阿拉伯一家三级护理医院中癫痫患者的社交焦虑、社会支持与生活质量
Cureus. 2023 Sep 18;15(9):e45447. doi: 10.7759/cureus.45447. eCollection 2023 Sep.
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Neonatal seizures: Etiologies, clinical characteristics, and radiological features: A cross-sectional study.新生儿惊厥:病因、临床特征和影像学特征:一项横断面研究。
Medicine (Baltimore). 2023 Sep 15;102(37):e35185. doi: 10.1097/MD.0000000000035185.
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Demographic and Clinical Predictors of Drug Response in Epileptic Children in Jeddah.
吉达癫痫儿童药物反应的人口统计学和临床预测因素
Biomedicines. 2023 Jul 30;11(8):2151. doi: 10.3390/biomedicines11082151.
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Characteristics of people with epilepsy in three Eastern African countries - a pooled analysis.三个东非国家癫痫患者的特征 - 一项汇总分析。
BMC Neurol. 2022 Aug 26;22(1):321. doi: 10.1186/s12883-022-02813-z.
5
Association between serum vitamin D levels and age in patients with epilepsy: a retrospective study from an epilepsy center in Saudi Arabia.血清维生素 D 水平与癫痫患者年龄的关系:来自沙特阿拉伯一家癫痫中心的回顾性研究。
Ann Saudi Med. 2022 Jul-Aug;42(4):262-268. doi: 10.5144/0256-4947.2022.262. Epub 2022 Aug 4.
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Clinical characteristics of patients with epilepsy attending primary health care.在基层医疗就诊的癫痫患者的临床特征。
Rev Neurol. 2022 Jul 1;75(1):7-12. doi: 10.33588/rn.7501.2022036.
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Seizure-related injuries in people with epilepsy: A cohort study from Saudi Arabia.癫痫患者的癫痫相关损伤:来自沙特阿拉伯的队列研究。
Epilepsia Open. 2022 Sep;7(3):422-430. doi: 10.1002/epi4.12615. Epub 2022 Jun 10.
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Epilepsy in Neurodegenerative Diseases: Related Drugs and Molecular Pathways.神经退行性疾病中的癫痫:相关药物与分子途径
Pharmaceuticals (Basel). 2021 Oct 18;14(10):1057. doi: 10.3390/ph14101057.
9
Prevalence of Medically Resistant Epilepsy in Saudi Arabia.沙特阿拉伯的耐药性癫痫患病率。
Neuroepidemiology. 2021;55(3):232-238. doi: 10.1159/000515743. Epub 2021 May 6.
10
Patients' knowledge about epilepsy in a tertiary medical center: A cross-sectional study from Riyadh, Saudi Arabia.沙特阿拉伯利雅得一家三级医疗中心的患者对癫痫的认知:一项横断面研究。
Epilepsy Behav. 2021 Mar;116:107395. doi: 10.1016/j.yebeh.2020.107395. Epub 2021 Feb 24.