• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Biventricular finite element modeling of the Acorn CorCap Cardiac Support Device on a failing heart.阿库恩（Acorn）穹顶型心包补片心脏支撑装置在衰竭心脏的双心室有限元建模。
Ann Thorac Surg. 2013 Jun;95(6):2022-7. doi: 10.1016/j.athoracsur.2013.02.032. Epub 2013 May 2.
2
Worldwide clinical experience with the CorCap Cardiac Support Device.CorCap心脏支持装置的全球临床经验。
J Card Fail. 2004 Dec;10(6 Suppl):S225-33. doi: 10.1016/j.cardfail.2004.09.006.
3
One-year clinical experience with the Acorn CorCap cardiac support device: results of a limited market release safety study in Italy and Sweden.使用橡果心脏支持装置的一年临床经验：意大利和瑞典有限市场投放安全性研究结果
Ital Heart J. 2005 Jan;6(1):59-65.
4
Clinical evaluation of the CorCap Cardiac Support Device in patients with dilated cardiomyopathy.CorCap心脏支持装置在扩张型心肌病患者中的临床评估。
Ann Thorac Surg. 2007 Oct;84(4):1226-35. doi: 10.1016/j.athoracsur.2007.03.095.
5
Sustained benefits of the CorCap Cardiac Support Device on left ventricular remodeling: three year follow-up results from the Acorn clinical trial.CorCap心脏支持装置对左心室重构的持续益处：橡果临床试验的三年随访结果。
Ann Thorac Surg. 2007 Oct;84(4):1236-42. doi: 10.1016/j.athoracsur.2007.03.096.
6
Global left ventricular remodeling with the Acorn Cardiac Support Device: hemodynamic and angiographic findings in dogs with heart failure.使用橡果心脏支持装置的全球左心室重塑：心力衰竭犬的血流动力学和血管造影结果
Heart Fail Rev. 2005 Jun;10(2):109-15. doi: 10.1007/s10741-005-4638-9.
7
Left ventricular histomorphometric findings in dogs with heart failure treated with the Acorn Cardiac Support Device.使用橡果心脏支持装置治疗的心力衰竭犬的左心室组织形态计量学研究结果
Heart Fail Rev. 2005 Jun;10(2):141-7. doi: 10.1007/s10741-005-4641-1.
8
Acute ventricular reduction with the acorn cardiac support device: effect on progressive left ventricular dysfunction and dilation in dogs with chronic heart failure.使用橡果心脏支持装置进行急性心室减容：对慢性心力衰竭犬进行性左心室功能障碍和扩张的影响。
J Card Surg. 2001 Mar-Apr;16(2):118-26. doi: 10.1111/j.1540-8191.2001.tb00496.x.
9
Mitral valve repair in heart failure: five-year follow-up from the mitral valve replacement stratum of the Acorn randomized trial.心力衰竭的二尖瓣修复： Acorn 随机试验二尖瓣置换层的 5 年随访。
J Thorac Cardiovasc Surg. 2011 Sep;142(3):569-74, 574.e1. doi: 10.1016/j.jtcvs.2010.10.051. Epub 2011 Jan 26.
10
Infarct size reduction and attenuation of global left ventricular remodeling with the CorCap cardiac support device following acute myocardial infarction in sheep.在绵羊急性心肌梗死后使用CorCap心脏支持装置减少梗死面积并减轻左心室整体重构。
Heart Fail Rev. 2005 Jun;10(2):125-39. doi: 10.1007/s10741-005-4640-2.

引用本文的文献

1
An epicardial delivery of nitroglycerine by active hydraulic ventricular support drug delivery system improves cardiac function in a rat model.主动液压心室支持药物输送系统经心外膜给药可改善大鼠模型的心脏功能。
Drug Deliv Transl Res. 2020 Feb;10(1):23-33. doi: 10.1007/s13346-019-00656-9.
2
Optimizing Epicardial Restraint and Reinforcement Following Myocardial Infarction: Moving Towards Localized, Biomimetic, and Multitherapeutic Options.优化心肌梗死后的心外膜约束与强化：迈向局部、仿生和多治疗方案
Biomimetics (Basel). 2019 Jan 17;4(1):7. doi: 10.3390/biomimetics4010007.
3
I-Wire Heart-on-a-Chip II: Biomechanical analysis of contractile, three-dimensional cardiomyocyte tissue constructs.我型线片上心脏II：收缩性三维心肌组织构建体的生物力学分析
Acta Biomater. 2017 Jan 15;48:79-87. doi: 10.1016/j.actbio.2016.11.010. Epub 2016 Nov 3.
4
Personalised computational cardiology: Patient-specific modelling in cardiac mechanics and biomaterial injection therapies for myocardial infarction.个性化计算心脏病学：心肌梗死心脏力学和生物材料注射治疗中的患者特异性建模。
Heart Fail Rev. 2016 Nov;21(6):815-826. doi: 10.1007/s10741-016-9528-9.
5
Distribution of normal human left ventricular myofiber stress at end diastole and end systole: a target for in silico design of heart failure treatments.正常人类左心室舒张末期和收缩末期肌纤维应力的分布：心力衰竭治疗计算机模拟设计的一个目标。
J Appl Physiol (1985). 2014 Jul 15;117(2):142-52. doi: 10.1152/japplphysiol.00255.2014. Epub 2014 May 29.
6
Applications of computational modeling in cardiac surgery.计算建模在心脏外科手术中的应用。
J Card Surg. 2014 May;29(3):293-302. doi: 10.1111/jocs.12332. Epub 2014 Apr 7.
7
Experimental and computational investigation of altered mechanical properties in myocardium after hydrogel injection.水凝胶注射后心肌力学性能改变的实验与计算研究
Ann Biomed Eng. 2014 Jul;42(7):1546-56. doi: 10.1007/s10439-013-0937-9. Epub 2013 Nov 23.

本文引用的文献

1
Material properties of CorCap passive cardiac support device.CorCap 被动心脏支持装置的材料性能。
Ann Thorac Surg. 2013 Jan;95(1):148-54. doi: 10.1016/j.athoracsur.2012.07.036. Epub 2012 Sep 13.
2
A coupled biventricular finite element and lumped-parameter circulatory system model of heart failure.心力衰竭的双心室耦合有限元与集总参数循环系统模型。
Comput Methods Biomech Biomed Engin. 2013;16(8):807-18. doi: 10.1080/10255842.2011.641121. Epub 2012 Jan 16.
3
Beneficial effects of the CorCap cardiac support device: five-year results from the Acorn Trial.CorCap 心脏支持装置的有益效果：Acorn 试验的五年结果。
J Thorac Cardiovasc Surg. 2012 May;143(5):1036-42. doi: 10.1016/j.jtcvs.2011.06.014. Epub 2011 Jul 16.
4
Effect of adjustable passive constraint on the failing left ventricle: a finite-element model study.可调式被动约束对衰竭左心室的影响：有限元模型研究。
Ann Thorac Surg. 2010 Jan;89(1):132-7. doi: 10.1016/j.athoracsur.2009.08.075.
5
A computationally efficient formal optimization of regional myocardial contractility in a sheep with left ventricular aneurysm.对一只患有左心室动脉瘤的绵羊的局部心肌收缩性进行计算高效的形式优化。
J Biomech Eng. 2009 Nov;131(11):111001. doi: 10.1115/1.3148464.
6
Sustained benefits of the CorCap Cardiac Support Device on left ventricular remodeling: three year follow-up results from the Acorn clinical trial.CorCap心脏支持装置对左心室重构的持续益处：橡果临床试验的三年随访结果。
Ann Thorac Surg. 2007 Oct;84(4):1236-42. doi: 10.1016/j.athoracsur.2007.03.096.
7
Clinical evaluation of the CorCap Cardiac Support Device in patients with dilated cardiomyopathy.CorCap心脏支持装置在扩张型心肌病患者中的临床评估。
Ann Thorac Surg. 2007 Oct;84(4):1226-35. doi: 10.1016/j.athoracsur.2007.03.095.
8
Cardiotropin-1 and myocardial strain change heterogeneously in cardiomyopathy.
J Surg Res. 2007 Aug;141(2):277-83. doi: 10.1016/j.jss.2006.12.539. Epub 2007 Jun 14.
9
Surgical ventricular remodeling: a balancing act on systolic and diastolic properties.外科心室重塑：收缩和舒张特性的平衡行为。
J Thorac Cardiovasc Surg. 2006 Sep;132(3):459-63. doi: 10.1016/j.jtcvs.2006.04.045.
10
Experimental and clinical studies with the Paracor cardiac restraint device.使用Paracor心脏约束装置的实验和临床研究。
Semin Thorac Cardiovasc Surg. 2005 Winter;17(4):364-8. doi: 10.1053/j.semtcvs.2005.09.006.

阿库恩（Acorn）穹顶型心包补片心脏支撑装置在衰竭心脏的双心室有限元建模。

Biventricular finite element modeling of the Acorn CorCap Cardiac Support Device on a failing heart.

机构信息

Department of Mechanical Engineering, University of Kentucky, Lexington, Kentucky, USA.

出版信息

Ann Thorac Surg. 2013 Jun;95(6):2022-7. doi: 10.1016/j.athoracsur.2013.02.032. Epub 2013 May 2.

DOI:10.1016/j.athoracsur.2013.02.032
PMID:23643546
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3702266/
Abstract

BACKGROUND

The Acorn CorCap Cardiac Support Device (CSD; Acorn Cardiovascular Inc, St. Paul, MN) is a woven polyester jacket that is placed around the heart and designed to reverse the progressive remodeling associated with dilated cardiomyopathy. However, the effects of the Acorn CSD on myofiber stress and ventricular function remain unknown. We tested the hypothesis that the Acorn CSD reduces end-diastolic (ED) myofiber stress.

METHODS

A previously described weakly coupled biventricular finite element (FE) model and circulatory model based on magnetic resonance images of a dog with dilated cardiomyopathy was used. Virtual applications of the CSD alone (Acorn), CSD with rotated fabric fiber orientation (rotated), CSD with 5% prestretch (tight), and CSD wrapped only around the left ventricle (LV; LV-only) were performed, and the effect on myofiber stress at ED and pump function was calculated.

RESULTS

The Acorn CSD has a large effect on ED myofiber stress in the LV free wall, with reductions of 55%, 79%, 92%, and 40% in the Acorn, rotated, tight, and LV-only cases, respectively. However, there is a tradeoff in which the Acorn CSD reduces stroke volume at LV end-diastolic pressure of 8 mm Hg by 23%, 25%, 30%, and 7%, respectively, in the Acorn, rotated, tight, and LV-only cases.

CONCLUSIONS

The Acorn CSD significantly reduces ED myofiber stress. However, CSD wrapped only around the LV was the only case with minimal negative effect on pump function. Findings suggest that LV-only CSD and Acorn fabric orientation should be optimized to allow maximal myofiber stress reduction with minimal reduction in pump function.

摘要

背景

Acorn CorCap 心脏支持装置（CSD；Acorn Cardiovascular Inc，明尼苏达州圣保罗）是一种环绕心脏的编织聚酯套，旨在逆转与扩张型心肌病相关的进行性重塑。然而，Acorn CSD 对心肌纤维压力和心室功能的影响尚不清楚。我们检验了 Acorn CSD 降低舒张末期（ED）心肌纤维压力的假设。

方法

使用先前描述的弱耦合双心室有限元（FE）模型和基于患有扩张型心肌病的狗的磁共振成像的循环模型。单独应用 CSD（Acorn）、纤维取向旋转的 CSD（旋转）、预拉伸 5%的 CSD（紧绷）和仅包裹左心室（LV；LV 仅）的 CSD 的虚拟应用，计算 ED 时心肌纤维压力和泵功能的变化。

结果

Acorn CSD 对 LV 游离壁 ED 心肌纤维压力有很大影响，Acorn、旋转、紧绷和 LV 仅的情况分别减少了 55%、79%、92%和 40%。然而，存在一个权衡，即 Acorn CSD 以 8 mmHg 的 LV 舒张末期压力分别减少 23%、25%、30%和 7%的每搏量。

结论

Acorn CSD 显著降低 ED 心肌纤维压力。然而，仅包裹 LV 的 CSD 是对泵功能影响最小的唯一情况。结果表明，LV 仅 CSD 和 Acorn 织物取向应进行优化，以允许最大程度地减少心肌纤维压力，同时最小化泵功能的降低。