Am J Gastroenterol. 2013 May;108(5):775-7. doi: 10.1038/ajg.2013.102.
Functional dyspepsia is a very common, distressful, and costly condition. New data indicate that heartburn and regurgitation occur frequently in functional dyspepsia, even after objective gastroesophageal reflux disease has been exhaustively excluded by appropriate testing. Arbitrarily excluding heartburn in functional dyspepsia studies appears misguided.
功能性消化不良是一种非常常见、令人痛苦且代价高昂的疾病。新数据表明，即使通过适当的测试详尽排除了胃食管反流病的客观存在，功能性消化不良患者仍经常出现烧心和反流。在功能性消化不良的研究中任意排除烧心症状似乎是有误导性的。
