Rosić B, Sulović V, Juznić N, Lazarević B, Milacić D, Vidanović M
Clinic of Gynecology and Obstetrics, School of Medicine, University of Belgrade, Yugoslavia.
Clin Exp Obstet Gynecol. 1990;17(1):31-5.
We have determined the levels of complement C3, C4 and immunoglobulin G, M, A in mothers' and cord blood serum. Parallelly properdin factor B and immunoglobulin G tests were done in urine samples. All estimations were performed on Immunochemistry Analyzer "Beckman". The investigations were made on 30 healthy pregnant women and 30 with arterial hypertension at the end of third trimester. In the mothers' serum C3 was not significantly changed. In the cord blood of healthy pregnant women it was 0.69 g/L. (SD 0.12) and in those with hypertension 0.38 g/L. (SD 0.15), which means significantly decreased. Complements C4 was not significantly increased in mothers' and cord blood serum. Properdin factor B was significantly increased in mothers' and cord blood serum (healthy pregnant women in serum 0.38 g/L., SD 0.07; with hypertension 0.48 g/L., SD 0.15; while in the cord blood serum of healthy women it was 0.14 g/L., SD 0.06; and hypertensive it was 0.22 g/L., SD 0.10). The same parameter was significantly decreased in the urine of healthy subjects 3.94 mg/L., SD 1.91; and in the hypertensive too, 2.42 mg/L., SD 0.90. The IgG level was significantly increased in the urine of healthy pregnant women 4.42 mg/L., SD 2.24; with hypertension 6.64 mg/L., SD 3.61. IgM was not significantly changed in mothers' and cord blood serum. IgA was significantly increased in the cord blood serum of healthy mothers', 0.02 g/L., SD 0.01, with hypertension 0.12 g/L., SD 0.05.
我们测定了母亲和脐带血血清中补体C3、C4以及免疫球蛋白G、M、A的水平。同时，对尿液样本进行了备解素因子B和免疫球蛋白G检测。所有检测均在“贝克曼”免疫化学分析仪上进行。研究对象为30名健康孕妇和30名妊娠晚期患有动脉高血压的孕妇。母亲血清中的C3无显著变化。健康孕妇脐带血中的C3为0.69 g/L（标准差0.12），高血压孕妇脐带血中的C3为0.38 g/L（标准差0.15），这意味着显著降低。母亲和脐带血血清中的补体C4无显著升高。母亲和脐带血血清中的备解素因子B显著升高（健康孕妇血清中为0.38 g/L，标准差0.07；高血压孕妇血清中为0.48 g/L，标准差0.15；健康孕妇脐带血血清中为0.14 g/L，标准差0.06；高血压孕妇脐带血血清中为0.22 g/L，标准差0.10）。健康受试者尿液中的该参数显著降低，为3.94 mg/L，标准差1.91；高血压受试者尿液中的该参数为2.42 mg/L，标准差0.90。健康孕妇尿液中的IgG水平显著升高，为4.42 mg/L，标准差2.24；高血压孕妇尿液中的IgG水平为6.64 mg/L，标准差3.61。母亲和脐带血血清中的IgM无显著变化。健康母亲脐带血血清中的IgA显著升高，为0.02 g/L，标准差0.01；高血压母亲脐带血血清中的IgA为0.12 g/L，标准差0.05。
