Shprecher David, Sloan Colgan T, Sederholm Benson
Department of Neurology, University of Utah, Salt Lake City, Utah, USA.
BMJ Case Rep. 2013 May 2;2013:bcr2013008997. doi: 10.1136/bcr-2013-008997.
Cyclobenzaprine is commonly used as a muscle relaxant and analgesic. Given its tricyclic properties, serotonin syndrome is a potential side effect of this drug. We report an unusual case of a patient who experienced symptoms of delirium and hyperkinetic movement disorders shortly after initiating treatment with cyclobenzaprine and oxycodone. Symptoms resolved within 48 h of discontinuing cyclobenzaprine. This case serves to remind clinicians to monitor for serotonin syndrome when initiating cyclobenzaprine, and when adding opiate or antidepressant medications to the regimen.
环苯扎林通常用作肌肉松弛剂和镇痛药。鉴于其三环类特性，血清素综合征是该药物的一种潜在副作用。我们报告了一例不寻常的病例，一名患者在开始使用环苯扎林和羟考酮治疗后不久出现谵妄和运动亢进性运动障碍症状。停用环苯扎林后48小时内症状缓解。该病例提醒临床医生在开始使用环苯扎林时以及在治疗方案中添加阿片类药物或抗抑郁药物时要监测血清素综合征。
