Depp Colin A, Kim Daniel H, de Dios Laura Vergel, Wang Vicki, Ceglowski Jennifer
Department of Psychiatry, University of California, San Diego, San Diego, California, USA ; San Diego Veterans Healthcare Administration, San Diego, California, USA.
J Dual Diagn. 2012 Jan 1;8(4):326-332. doi: 10.1080/15504263.2012.723318.
Patient reported mood charts are frequently used in management of bipolar disorder. Although mood charts have recently been programmed in electronic devices such as mobile phones, little is known about the impact of the method of data capture on the psychometric properties and validity of these data.
In an ongoing pilot study, a sample of outpatients with bipolar disorder were randomized to either complete mood charts on a mobile phone or a standard paper-and-pencil mood chart as part of a 12 week-intervention (primary outcomes for the trial await study completion). We compared these conditions across single item rating of mood state, and we hypothesized that mobile phone based data capture would produce greater compliance to mood ratings, variability between and within participants, and concurrent validity with blinded clinician-rated affective symptom severity.
A total of 56 participants were randomized and 40 participants were included in the analyses. There were no significant differences between conditions on demographic or clinical variables. The rate of compliance was significantly higher in paper-and-pencil versus mobile phone ratings. Ratings demonstrated significantly more variability within individuals in the mobile phone condition. Mobile phone mood ratings were significantly correlated with clinician-rated depressive symptom severity across the study and with manic symptom severity at the Week 6 assessment, whereas paper-and-pencil ratings were not significantly associated with clinician-rated depression or mania.
Although preliminary, our results suggest a lower rate of compliance with mobile phones compared to paper-and-pencil daily mood rating in bipolar disorder, yet a greater ability to capture variability and concurrent validity in quantifying affective symptoms. This clinical trial is registered at http://www.clinicaltrials.gov as NCT01670123.
患者报告的情绪图表常用于双相情感障碍的管理。尽管情绪图表最近已被编程到诸如手机等电子设备中，但对于数据采集方法对这些数据的心理测量特性和有效性的影响知之甚少。
在一项正在进行的试点研究中，将双相情感障碍门诊患者样本随机分为通过手机完成情绪图表或使用标准纸笔情绪图表，作为为期12周干预的一部分（该试验的主要结局有待研究完成）。我们比较了这些条件下情绪状态的单项评分，并假设基于手机的数据采集将在情绪评分的依从性、参与者之间和内部的变异性以及与盲法临床医生评定的情感症状严重程度的同时效度方面产生更大效果。
共有56名参与者被随机分组，40名参与者纳入分析。在人口统计学或临床变量方面，各条件之间无显著差异。纸笔评分的依从率显著高于手机评分。在手机条件下，评分显示个体内部的变异性显著更大。在整个研究过程中，手机情绪评分与临床医生评定的抑郁症状严重程度显著相关，在第6周评估时与躁狂症状严重程度显著相关，而纸笔评分与临床医生评定的抑郁或躁狂无显著关联。
尽管是初步的，但我们的结果表明，与双相情感障碍患者每日纸笔情绪评分相比，手机的依从率较低，但在量化情感症状方面捕捉变异性和同时效度的能力更强。该临床试验已在http://www.clinicaltrials.gov注册，注册号为NCT01670123。
