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本文引用的文献

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Treatment adherence following national antiretroviral rollout in South Africa.南非全国推行抗逆转录病毒疗法后的治疗依从性。
Afr J AIDS Res. 2010 Sep;9(3):235-47. doi: 10.2989/16085906.2010.530177.
2
Atazanavir concentration in hair is the strongest predictor of outcomes on antiretroviral therapy.发中阿扎那韦浓度是抗逆转录病毒治疗结果的最强预测因子。
Clin Infect Dis. 2011 May;52(10):1267-75. doi: 10.1093/cid/cir131.
3
Real-time electronic adherence monitoring is feasible, comparable to unannounced pill counts, and acceptable.实时电子药物依从性监测是可行的,与未告知的药丸计数具有可比性,并且是可以接受的。
AIDS Behav. 2012 Feb;16(2):375-82. doi: 10.1007/s10461-011-9933-y.
4
Measuring adherence to antiretroviral treatment in resource-poor settings: the feasibility of collecting routine data for key indicators.在资源匮乏环境下测量抗逆转录病毒治疗的依从性:收集关键指标常规数据的可行性。
BMC Health Serv Res. 2010 Feb 19;10:43. doi: 10.1186/1472-6963-10-43.
5
Measuring adherence to antiretroviral treatment in resource-poor settings: the clinical validity of key indicators.在资源匮乏环境下衡量抗逆转录病毒治疗的依从性:关键指标的临床有效性。
BMC Health Serv Res. 2010 Feb 19;10:42. doi: 10.1186/1472-6963-10-42.
6
Pharmacogenetics of antiretrovirals.抗逆转录病毒药物的药物遗传学。
Antiviral Res. 2010 Jan;85(1):190-200. doi: 10.1016/j.antiviral.2009.09.001. Epub 2009 Sep 8.
7
Clinical prognostic value of RNA viral load and CD4 cell counts during untreated HIV-1 infection--a quantitative review.未经治疗的HIV-1感染期间RNA病毒载量和CD4细胞计数的临床预后价值——一项定量综述
PLoS One. 2009 Jun 17;4(6):e5950. doi: 10.1371/journal.pone.0005950.
8
Protease inhibitor levels in hair strongly predict virologic response to treatment.头发中的蛋白酶抑制剂水平能有力预测对治疗的病毒学反应。
AIDS. 2009 Feb 20;23(4):471-8. doi: 10.1097/QAD.0b013e328325a4a9.
9
Ethical aspects of genome diversity research: genome research into cultural diversity or cultural diversity in genome research?基因组多样性研究的伦理问题:是对文化多样性进行基因组研究,还是基因组研究中的文化多样性?
Med Health Care Philos. 2009 Mar;12(1):25-34. doi: 10.1007/s11019-008-9147-x. Epub 2008 Jul 1.
10
Pharmacy refill adherence compared with CD4 count changes for monitoring HIV-infected adults on antiretroviral therapy.在接受抗逆转录病毒治疗的HIV感染成人中,比较药房续方依从性与CD4细胞计数变化以进行监测。
PLoS Med. 2008 May 20;5(5):e109. doi: 10.1371/journal.pmed.0050109.

南非样本中与为医学研究提供毛发样本相关的反应、信念和担忧:一种定性研究方法

Reactions, beliefs and concerns associated with providing hair specimens for medical research among a South African sample: a qualitative approach.

作者信息

Coetzee Bronwyne, Kagee Ashraf, Tomlinson Mark, Warnich Louise, Ikediobi Ogechi

机构信息

Stellenbosch University, Department of Psychology, Stellenbosch, South Africa.

出版信息

Future Virol. 2012 Nov 1;7(11):1135-1142. doi: 10.2217/fvl.12.100.

DOI:10.2217/fvl.12.100
PMID:23646064
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3640774/
Abstract

In order to optimize treatment outcome among antiretroviral therapy users, there is a strong imperative to engage in continued monitoring and maintenance of therapeutic drug levels in patients. The aim of this study was to document the perspectives, beliefs, and concerns of South African antiretroviral therapy users providing hair specimens to determine antiretroviral drug levels. Twenty-one women living with HIV were recruited from a community health center in the Western Cape. Interviews were recorded and transcribed, and analyzed using Atlas.ti version 6. Although participants identified several cultural beliefs influencing their decision to provide hair specimens for drug level measurement, nearly all agreed that they would be willing to do so if provided with enough information by the researcher.

摘要

为了优化抗逆转录病毒疗法使用者的治疗效果,对患者进行持续监测并维持治疗药物水平至关重要。本研究的目的是记录南非抗逆转录病毒疗法使用者对于提供头发样本以测定抗逆转录病毒药物水平的观点、信念和担忧。从西开普省的一个社区卫生中心招募了21名感染艾滋病毒的女性。访谈进行了录音和转录,并使用Atlas.ti 6版本进行分析。尽管参与者指出了几种文化信念影响她们决定提供头发样本进行药物水平测量,但几乎所有人都同意,如果研究人员提供足够的信息,她们愿意这样做。