Van Dyk Alta C
a University of South Africa (UNISA) , Department of Psychology , PO Box 392 , Pretoria , 0003 , South Africa.
Afr J AIDS Res. 2010 Sep;9(3):235-47. doi: 10.2989/16085906.2010.530177.
The national antiretroviral (ARV) programme in South Africa commenced in 2004. ARV drugs became readily available to all South Africans due to the concerted efforts of 'access to all' campaigns. This study investigates medication adherence among a sample of South Africans after the ARV rollout in order to gain insight into the adherence challenges they face. A semi-structured questionnaire was completed by 439 participants from across the country. The results show that only 40% of the respondents were able to reach the optimum adherence level of 90% or above. The patients who displayed below-optimum adherence often had not been part of an ARV-preparation programme, did not have HIV-treatment supporters, lacked general knowledge about drug adherence, and felt unsupported by healthcare providers in their day-to-day effort to adhere to their medications. They often had no money for food or transportation, ran out of ARVs for various reasons, suffered from HIV-treatment fatigue, battled with depression, abused alcohol, could not disclose to sexual partners that they were on ARVs, and often had to hide or skip ARV dosages because they feared stigma and discrimination. Suggestions to assist patients to adhere to their ARV medications are made.
南非的国家抗逆转录病毒（ARV）计划始于2004年。由于“全民可及”运动的共同努力，抗逆转录病毒药物已能让所有南非人轻易获取。本研究调查了抗逆转录病毒药物推广后南非部分人群的药物依从性情况，以便深入了解他们所面临的依从性挑战。来自全国各地的439名参与者完成了一份半结构化问卷。结果显示，只有40%的受访者能够达到90%及以上的最佳依从水平。依从性未达最佳的患者往往没有参加过抗逆转录病毒药物准备计划，没有艾滋病治疗支持者，缺乏药物依从性的常识，并且在日常坚持服药方面感觉未得到医疗服务提供者的支持。他们常常没有钱购买食物或支付交通费用，因各种原因用完了抗逆转录病毒药物，患有艾滋病治疗疲劳症，与抑郁症作斗争，酗酒，无法向性伴侣透露自己正在服用抗逆转录病毒药物，并且常常因为害怕耻辱和歧视而不得不隐藏或跳过抗逆转录病毒药物剂量。文中还提出了帮助患者坚持服用抗逆转录病毒药物的建议。
