Department of Obstetrics and Gynecology, Faculty of Medicine, Menofyia University , Shibin Elkom , Egypt.
Climacteric. 2014 Feb;17(1):55-9. doi: 10.3109/13697137.2013.801014. Epub 2013 Jun 28.
To investigate whether three-dimensional saline-infusion transvaginal sonohysterography can replace hysteroscopy in the detection of intrauterine lesions in women with perimenopausal bleeding.
This study was carried out at the Department of Obstetrics and Gynecology, Menofyia University Hospital in Egypt. Fifty women who presented with perimenopausal bleeding and fulfilled the inclusion criteria were recruited for the study. Three-dimensional sonohysterography was performed followed by hysteroscopy for all women. Results were tabulated and statistically analyzed. The accuracy of both techniques was calculated in terms of sensitivity, specificity, positive and negative predictive values.
The mean age of women enrolled was 47.5 ± 5.61 years and the mean body mass index was 28.13 ± 2.91 kg/m(2). Three-dimensional sonohysterography detected no abnormality in 26 women but hysteroscopy only detected 24 with no abnormality. Compared to hysteroscopy, three-dimensional sonohysterography has sensitivities of 100% and 92% in the detection of endometrial polyps and submucous fibroids, respectively. The specificity of sonohysterography for both lesions was 100%. The sensitivity and specificity for other lesions exceeded 95%.
Three-dimensional sonohysterosonography may be considered as an effective alternative to hysteroscopy in the assessment of the uterine cavity for any woman with perimenopausal bleeding.
研究三维盐水灌注经阴道超声检查（3D-SIS）是否可以替代宫腔镜检查，用于检测围绝经期出血患者的宫腔内病变。
本研究在埃及 Menofyia 大学医院妇产科进行。招募了 50 名符合纳入标准的围绝经期出血患者进行本研究。所有患者均行 3D-SIS 检查，随后行宫腔镜检查。对结果进行制表和统计学分析。两种技术的准确性均以灵敏度、特异性、阳性和阴性预测值来计算。
入组患者的平均年龄为 47.5 ± 5.61 岁，平均体重指数（BMI）为 28.13 ± 2.91 kg/m²。3D-SIS 检查发现 26 名患者无异常，但宫腔镜仅发现 24 名无异常。与宫腔镜相比，3D-SIS 检查对子宫内膜息肉和黏膜下肌瘤的灵敏度分别为 100%和 92%。3D-SIS 对这两种病变的特异性均为 100%。其他病变的灵敏度和特异性均超过 95%。
对于任何围绝经期出血的女性，3D-SIS 可作为评估宫腔的一种有效替代方法，替代宫腔镜检查。
