电解质紊乱和窒息对新生儿听力的影响及后果。
The effects and outcomes of electrolyte disturbances and asphyxia on newborns hearing.
作者信息
Liang Chun, Hong Qi, Jiang Tao-Tao, Gao Yan, Yao Xiao-Fang, Luo Xiao-Xing, Zhuo Xiu-Hui, Shinn Jennifer B, Jones Raleigh O, Zhao Hong-Bo, Lu Guang-Jin
机构信息
Maternal and Child Health Care Hospital of Baoan, Shenzhen 518133, PR China.
出版信息
Int J Pediatr Otorhinolaryngol. 2013 Jul;77(7):1072-6. doi: 10.1016/j.ijporl.2013.03.031. Epub 2013 May 4.
OBJECTIVE
To determine the effect of electrolyte disturbances (ED) and asphyxia on infant hearing and hearing outcomes.
STUDY DESIGN
We conducted newborn hearing screening with transient evoked otoacoustic emission (TEOAE) test on a large scale (>5000 infants). The effects of ED and asphyxia on infant hearing and hearing outcomes were evaluated.
RESULT
The pass rate of TEOAE test was significantly reduced in preterm infants with ED (83.1%, multiple logistic regression analysis: P<0.01) but not in full-term infants with ED (93.6%, P=0.41). However, there was no significant reduction in the pass rate in infants with asphyxia (P=0.85). We further found that hypocalcaemia significantly reduced the pass rate of TEOAE test (86.8%, P<0.01). In the follow-up recheck at 3 months of age, the pass rate remained low (44.4%, P<0.01).
CONCLUSION
ED is a high-risk factor for preterm infant hearing. Hypocalcaemia can produce more significant impairment with a low recovery rate.
目的
确定电解质紊乱（ED）和窒息对婴儿听力及听力结果的影响。
研究设计
我们采用瞬态诱发耳声发射（TEOAE）测试对超过5000名婴儿进行了大规模新生儿听力筛查。评估了ED和窒息对婴儿听力及听力结果的影响。
结果
患有ED的早产儿TEOAE测试通过率显著降低（83.1%，多因素逻辑回归分析：P<0.01），但患有ED的足月儿通过率未显著降低（93.6%，P=0.41）。然而，窒息婴儿的通过率没有显著降低（P=0.85）。我们进一步发现低钙血症显著降低了TEOAE测试的通过率（86.8%，P<0.01）。在3个月龄的随访复查中，通过率仍然很低（44.4%，P<0.01）。
结论
ED是早产儿听力的高危因素。低钙血症可产生更显著的损害且恢复率低。
Zotero 插件