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糖尿病患者唾液pH值、龋齿发病率与牙周状况的相关性:一项横断面研究

Correlation of Salivary pH, Incidence of Dental Caries and Periodontal Status in Diabetes Mellitus Patients: A Cross-sectional Study.

作者信息

Seethalakshmi C, Reddy R C Jagat, Asifa Nisha, Prabhu S

机构信息

Senior Lecturer, Department of Oral Medicine and Radiology, Chettinad Dental College and Research Institute , Kelambakkam, Chennai, India .

Professor and Head, Department of Oral Medicine and Radiology, Chettinad Dental College and Research Institute , Kelambakkam, Chennai, India .

出版信息

J Clin Diagn Res. 2016 Mar;10(3):ZC12-4. doi: 10.7860/JCDR/2016/16310.7351. Epub 2016 Mar 1.

DOI:10.7860/JCDR/2016/16310.7351
PMID:27134992
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4843377/
Abstract

INTRODUCTION

Diabetes mellitus is a chronic disease affecting many parts of the body. A number of oral diseases have been associated with diabetes mellitus with an increased risk of dental caries and periodontal disease.

AIM

The aim of the study was to evaluate the salivary pH and incidence of dental caries and periodontal status in diabetes mellitus compared to that of the normal subjects.

MATERIALS AND METHODS

The study population consisted of 40 patients divided into 2 groups with group I comprising of 20 known diabetes mellitus patients and group II comprising of 20 non diabetic subjects as control group. The pH of the saliva was determined using a digital pH meter. Dental caries and periodontal status were assessed by DMFT and PDI indices respectively.

RESULTS

There was a decrease in the mean salivary pH of 6.51 in the study group, compared to the normal mean salivary pH of 7.88 in the control group. The mean DMFT index was higher in the study group (8.10) when compared to that of control group (1.15). The mean PDI score was also higher in the study group (4.0) as compared to that of the control group (0.45).

CONCLUSION

The results of the present study concluded that there was a significant relationship between the diabetes mellitus and increased incidence of dental caries and periodontitis and there was also a significant reduction in the salivary pH in diabetes mellitus patients, compared to that of non diabetic subjects.

摘要

引言

糖尿病是一种影响身体多个部位的慢性疾病。许多口腔疾病都与糖尿病相关,患龋齿和牙周疾病的风险会增加。

目的

本研究的目的是评估糖尿病患者唾液pH值、龋齿发病率和牙周状况,并与正常受试者进行比较。

材料与方法

研究人群包括40名患者,分为两组,第一组由20名已知糖尿病患者组成,第二组由20名非糖尿病受试者作为对照组。使用数字pH计测定唾液pH值。分别通过DMFT和PDI指数评估龋齿和牙周状况。

结果

研究组唾液平均pH值为6.51,低于对照组正常唾液平均pH值7.88。研究组的平均DMFT指数(8.10)高于对照组(1.15)。研究组的平均PDI评分(4.0)也高于对照组(0.45)。

结论

本研究结果表明,糖尿病与龋齿和牙周炎发病率增加之间存在显著关系,与非糖尿病受试者相比,糖尿病患者的唾液pH值也显著降低。

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2
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Adv Med Sci. 2014 Mar;59(1):126-31. doi: 10.1016/j.advms.2014.01.002. Epub 2014 Mar 15.
3
Local levels of inflammatory mediators in uncontrolled type 2 diabetic subjects with chronic periodontitis.患有慢性牙周炎的未控制的2型糖尿病患者体内炎症介质的局部水平。
J Clin Periodontol. 2014 Jan;41(1):11-8. doi: 10.1111/jcpe.12179. Epub 2013 Nov 11.
4
Salivary pH: A diagnostic biomarker.唾液酸碱度:一种诊断生物标志物。
J Indian Soc Periodontol. 2013 Jul;17(4):461-5. doi: 10.4103/0972-124X.118317.
5
Evaluation of Salivary Profile among Adult Type 2 Diabetes Mellitus Patients in South India.印度南部成年2型糖尿病患者唾液特征评估
J Clin Diagn Res. 2013 Aug;7(8):1592-5. doi: 10.7860/JCDR/2013/5749.3232. Epub 2013 Aug 1.
6
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7
Caries experience among children with type 1 diabetes in Kuwait.科威特1型糖尿病儿童的龋齿患病情况。
Pediatr Dent. 2012 Nov-Dec;34(7):468-72.
8
Dental caries and salivary alterations in Type I Diabetes.1型糖尿病中的龋齿与唾液改变
J Clin Pediatr Dent. 2011 Winter;36(2):181-4. doi: 10.17796/jcpd.36.2.x436ln878221g364.
9
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Sultan Qaboos Univ Med J. 2011 May;11(2):179-86. Epub 2011 May 15.
10
Possible involvement of advanced glycation end products in periodontal diseases.晚期糖基化终产物在牙周病中的可能作用。
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