Pandit Nymphea, Gupta Rajan, Bansal Aarti
Department of Periodontology, D.A.V. (C) Dental College, Yamuna Nagar, Haryana, India.
Indian J Dent Res. 2012 Nov-Dec;23(6):778-83. doi: 10.4103/0970-9290.111259.
A randomized clinical trail was designed to compare the efficacy of two commercially available desensitizing agents (fluoride varnish containing 6% sodium fluoride and 6% calcium fluoride and a gel containing 6% potassium nitrate and 0.11% fluoride ions) in the treatment of dentinal hypersensitivity.
Randomized clinical trial.
Twenty-one patients were selected. Subjects were evaluated using three different stimuli, i.e., tactile test, air blast test and cold water test. They were then randomly divided into two groups. Patients in group I were treated with fluoride varnish and group II patients were treated with gel containing 6% potassium nitrate and 0.11% fluoride ions. The patients were examined at baseline, immediately after application of the agent, at 1 week, 1 month and 3 months interval.
Statistical analysis was done using unpaired "t" test, paired "t" test and Chi-square test with Yate's correction.
The results were analyzed; it was seen that patients treated in group I showed significantly better results compared to group II patients at 1 month and 3 months interval. Teeth which required repeat dose and those which did not require repeat dose were comparable in number.
Both the agents showed significant reduction in sensitivity at all time intervals compared to baseline. A comparatively significant reduction in sensitivity score was seen in patients treated with fluoride varnish and it appeared to be more effective in providing long-term relief against all the three test stimuli. Teeth with initial high sensitivity score required repeat doses, which was comparable for both the groups.
设计一项随机临床试验,比较两种市售脱敏剂(含6%氟化钠和6%氟化钙的氟化物清漆以及含6%硝酸钾和0.11%氟离子的凝胶)治疗牙本质过敏症的疗效。
随机临床试验。
选取21名患者。使用三种不同刺激(即触觉测试、气喷测试和冷水测试)对受试者进行评估。然后将他们随机分为两组。第一组患者用氟化物清漆治疗,第二组患者用含6%硝酸钾和0.11%氟离子的凝胶治疗。在基线、应用药物后即刻、1周、1个月和3个月间隔时对患者进行检查。
采用不成对“t”检验、配对“t”检验和经Yates校正的卡方检验进行统计分析。
对结果进行分析;发现在1个月和3个月间隔时,第一组治疗的患者与第二组患者相比显示出明显更好的结果。需要重复给药的牙齿和不需要重复给药的牙齿数量相当。
与基线相比,两种药物在所有时间间隔均显示出敏感性显著降低。用氟化物清漆治疗的患者敏感性评分相对显著降低,并且在针对所有三种测试刺激提供长期缓解方面似乎更有效。初始敏感性评分高的牙齿需要重复给药,两组情况相当。