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利用电子个人健康记录识别有阿司匹林诱发胃肠道出血风险的患者。

Use of electronic personal health records to identify patients at risk for aspirin-induced gastrointestinal bleeding.

作者信息

Jackson Anita N, Kogut Stephen

机构信息

Department of Pharmacy Practice, University of Rhode Island College of Pharmacy, Kingston, RI, USA.

出版信息

Consult Pharm. 2013 May;28(5):313-8. doi: 10.4140/TCP.n.2013.313.

Abstract

OBJECTIVE(S): The aim of this paper is to describe the utility of electronic personal health records (ePHRs) to identify patients with potential risk factors for aspirin-induced upper gastrointestinal bleeding (UGIB).

SETTING

ER-Card, LLC. a for-profit ePHR company located in Rhode Island from October 2008 to May 2010.

PRACTICE DESCRIPTION

Clinical pharmacists reviewed the records of 615 patients enrolled in an ePHR service. Records included patient self-report of all known medical conditions, current prescription medications, and self-care therapies utilized.

PRACTICE INNOVATION

Pharmacists reviewed ePHR profiles for actual or potential medication-related problems. Patients taking low-dose aspirin (81 mg-325 mg daily) were screened for known additional risk factors for aspirin-induced UGIB. Patients identified were notified to contact their provider for information and/or providers were contacted directly by pharmacists with therapy recommendations.

MAIN OUTCOME MEASURE(S): Number of patients at increased risk for aspirin-induced UGIB as a result of concomitant medications.

RESULTS

Ninety-seven patients (16% of total records screened) with an average age of 72.1 years had risk factors for aspirin induced UGIB. In addition to daily aspirin therapy patients reported regular use of nonsteroidal anti-inflammatory drugs or cyclooxygenase-2 inhibitors (38%), other antiplatelet agents (22%), anticoagulants (24%), corticosteroids (4%), or a combination of these medications (12%). None of the patients included in this analysis reported use of prescribed or overthe-counter gastroprotective therapy (such as proton-pump inhibitors or histamine-2 receptor antagonists).

CONCLUSION

Pharmacist screening of patient self-reported health information as part of an ePHR service can result in the detection of a significant number of patients at increased risk for aspirin-induced UGIB.

摘要

目的

本文旨在描述电子个人健康记录(ePHR)在识别有阿司匹林诱发上消化道出血(UGIB)潜在风险因素患者方面的作用。

背景

ER-Card有限责任公司,一家位于罗德岛的盈利性ePHR公司,研究时间为2008年10月至2010年5月。

实践描述

临床药师查阅了615名参加ePHR服务患者的记录。记录包括患者对所有已知医疗状况、当前处方药和所采用自我护理疗法的自我报告。

实践创新

药师审查ePHR档案以查找实际或潜在的药物相关问题。对服用低剂量阿司匹林(每日81毫克 - 325毫克)的患者筛查已知的阿司匹林诱发UGIB的其他风险因素。识别出的患者会被告知联系其医疗服务提供者获取信息,和/或药师会直接联系医疗服务提供者并给出治疗建议。

主要结局指标

因合并用药导致阿司匹林诱发UGIB风险增加的患者数量。

结果

97名患者(占筛查总记录的16%)平均年龄为72.1岁,有阿司匹林诱发UGIB的风险因素。除每日服用阿司匹林治疗外,患者报告经常使用非甾体抗炎药或环氧化酶 - 2抑制剂(38%)、其他抗血小板药物(22%)、抗凝剂(24%)、皮质类固醇(4%)或这些药物的组合(12%)。该分析中的患者均未报告使用过处方或非处方胃保护疗法(如质子泵抑制剂或组胺 - 2受体拮抗剂)。

结论

作为ePHR服务的一部分,药师对患者自我报告的健康信息进行筛查,可检测出大量有阿司匹林诱发UGIB风险增加的患者。

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Risk of upper gastrointestinal bleeding from different drug combinations.不同药物组合致上消化道出血的风险。
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