Jackson Anita N, Kogut Stephen
Department of Pharmacy Practice, University of Rhode Island College of Pharmacy, Kingston, RI, USA.
Consult Pharm. 2013 May;28(5):313-8. doi: 10.4140/TCP.n.2013.313.
OBJECTIVE(S): The aim of this paper is to describe the utility of electronic personal health records (ePHRs) to identify patients with potential risk factors for aspirin-induced upper gastrointestinal bleeding (UGIB).
ER-Card, LLC. a for-profit ePHR company located in Rhode Island from October 2008 to May 2010.
Clinical pharmacists reviewed the records of 615 patients enrolled in an ePHR service. Records included patient self-report of all known medical conditions, current prescription medications, and self-care therapies utilized.
Pharmacists reviewed ePHR profiles for actual or potential medication-related problems. Patients taking low-dose aspirin (81 mg-325 mg daily) were screened for known additional risk factors for aspirin-induced UGIB. Patients identified were notified to contact their provider for information and/or providers were contacted directly by pharmacists with therapy recommendations.
MAIN OUTCOME MEASURE(S): Number of patients at increased risk for aspirin-induced UGIB as a result of concomitant medications.
Ninety-seven patients (16% of total records screened) with an average age of 72.1 years had risk factors for aspirin induced UGIB. In addition to daily aspirin therapy patients reported regular use of nonsteroidal anti-inflammatory drugs or cyclooxygenase-2 inhibitors (38%), other antiplatelet agents (22%), anticoagulants (24%), corticosteroids (4%), or a combination of these medications (12%). None of the patients included in this analysis reported use of prescribed or overthe-counter gastroprotective therapy (such as proton-pump inhibitors or histamine-2 receptor antagonists).
Pharmacist screening of patient self-reported health information as part of an ePHR service can result in the detection of a significant number of patients at increased risk for aspirin-induced UGIB.
本文旨在描述电子个人健康记录(ePHR)在识别有阿司匹林诱发上消化道出血(UGIB)潜在风险因素患者方面的作用。
ER-Card有限责任公司,一家位于罗德岛的盈利性ePHR公司,研究时间为2008年10月至2010年5月。
临床药师查阅了615名参加ePHR服务患者的记录。记录包括患者对所有已知医疗状况、当前处方药和所采用自我护理疗法的自我报告。
药师审查ePHR档案以查找实际或潜在的药物相关问题。对服用低剂量阿司匹林(每日81毫克 - 325毫克)的患者筛查已知的阿司匹林诱发UGIB的其他风险因素。识别出的患者会被告知联系其医疗服务提供者获取信息,和/或药师会直接联系医疗服务提供者并给出治疗建议。
因合并用药导致阿司匹林诱发UGIB风险增加的患者数量。
97名患者(占筛查总记录的16%)平均年龄为72.1岁,有阿司匹林诱发UGIB的风险因素。除每日服用阿司匹林治疗外,患者报告经常使用非甾体抗炎药或环氧化酶 - 2抑制剂(38%)、其他抗血小板药物(22%)、抗凝剂(24%)、皮质类固醇(4%)或这些药物的组合(12%)。该分析中的患者均未报告使用过处方或非处方胃保护疗法(如质子泵抑制剂或组胺 - 2受体拮抗剂)。
作为ePHR服务的一部分,药师对患者自我报告的健康信息进行筛查,可检测出大量有阿司匹林诱发UGIB风险增加的患者。