慢性活动性胸段结节病患者钙重吸收的肾小管最大重吸收量

The tubular maximum for calcium reabsorption in patients with chronic active thoracic sarcoidosis.

作者信息

Broulik P D, Votava V, Pacovsky V

机构信息

Third Dept of Internal Medicine, Charles University, Faculty of Medicine, Prague, Czechoslovakia.

出版信息

Eur Respir J. 1990 Apr;3(4):447-9.

PMID:2365038

Abstract

The tubular maximum for calcium reabsorption (TmCa) was evaluated in 52 patients with chronic active thoracic sarcoidosis. Hypercalcaemia was found in five patients (9.6%). The mean serum calcium value of 2.54 +/- 0.18 mmol.l-1 in patients with sarcoidosis was significantly higher than that obtained in the control group (2.42 +/- 0.11 mmol.l-1). The mean TmCa in patients with sarcoidosis (2.11 +/- 0.26 mmol.l-1 glomerular filtrate (GF] was not statistically different from the mean TmCa for the group of healthy subjects (2.18 +/- 0.23 mmol.l-1 GF). Urinary sodium corrected TmCa in both groups of patients was affected in a similar way. Our study demonstrates for the first time that there is no increase in TmCa in patients with chronic active thoracic sarcoidosis. Hypercalcaemia is not a result of an increased TmCa.

摘要

对52例慢性活动性胸段结节病患者的钙重吸收肾小管最大量（TmCa）进行了评估。5例患者（9.6%）出现高钙血症。结节病患者的血清钙均值为2.54±0.18mmol·l⁻¹，显著高于对照组（2.42±0.11mmol·l⁻¹）。结节病患者的平均TmCa（2.11±0.26mmol·l⁻¹肾小球滤过液（GF））与健康受试者组的平均TmCa（2.18±0.23mmol·l⁻¹GF）无统计学差异。两组患者尿钠校正后的TmCa受到的影响相似。我们的研究首次表明，慢性活动性胸段结节病患者的TmCa没有增加。高钙血症不是TmCa增加的结果。