Department of Public Health and Community Medicine/Primary Health Care, University of Gothenburg, Gothenburg, Sweden.
Int J Gen Med. 2013 Apr 24;6:307-15. doi: 10.2147/IJGM.S42201. Print 2013.
To investigate possible association between mental stress and psychosomatic symptoms, socioeconomic status, lifestyle, as well as incident mortality in a middle-aged female population followed over 37 years.
A prospective observational study initiated in 1968-1969, including 1462 women aged 60, 54, 50, 46, and 38 years, with follow-ups in 1974-1975, 1980-1981, and 2000-2001, was performed. Measures included self-reported mental stress as well as psychosomatic symptoms and smoking, physical activity, total cholesterol, S-triglycerides, body mass index, waist-hip ratio, blood pressure, socioeconomic status and mortality.
Smoking, not being single, and not working outside home were strongly associated with reported mental stress at baseline. Women who reported high mental stress in 1968-1969 were more likely to report presence of abdominal symptoms (odds ratio [OR] = 1.85, 95% confidence interval [CI]: 1.39-2.46), headache/migraine (OR = 2.04, 95% CI: 1.53-2.72), frequent infections (OR = 1.75, 95% CI: 1.14-2.70), and musculoskeletal symptoms (OR = 1.70, 95% CI: 1.30-2.23) than women who did not report mental stress. Women without these symptoms at baseline 1968-1969, but with perceived mental stress were more likely to subsequently report incident abdominal symptoms (OR = 2.15, 95% CI: 1.39-3.34), headache/migraine (OR = 2.27, 95% CI: 1.48-3.48) and frequent infections (OR = 2.21, 95% CI: 1.12-4.36) in 1974-1975 than women without mental stress in 1968-1969. There was no association between perceived mental stress at baseline and mortality over 37 years of follow-up.
Women reporting mental stress had a higher frequency of psychosomatic symptoms than women who did not report these symptoms. Not working outside home and smoking rather than low socioeconomic status per se was associated with higher stress levels. Perception of high mental stress was not associated with increased mortality.
在一项随访 37 年的中年女性人群中,调查精神压力与心身症状、社会经济地位、生活方式以及发病死亡率之间的可能关联。
这是一项前瞻性观察研究,于 1968-1969 年启动,纳入了 1462 名年龄为 60、54、50、46 和 38 岁的女性,随后分别于 1974-1975 年、1980-1981 年和 2000-2001 年进行了随访。测量指标包括精神压力自评以及心身症状、吸烟、体力活动、总胆固醇、血清三酰甘油、体重指数、腰臀比、血压、社会经济地位和死亡率。
在基线时,吸烟、非单身状态和不在家庭以外工作与报告的精神压力高度相关。1968-1969 年报告精神压力高的女性更有可能报告存在腹部症状(比值比 [OR] = 1.85,95%置信区间 [CI]:1.39-2.46)、头痛/偏头痛(OR = 2.04,95% CI:1.53-2.72)、频繁感染(OR = 1.75,95% CI:1.14-2.70)和肌肉骨骼症状(OR = 1.70,95% CI:1.30-2.23),而非报告精神压力的女性。1968-1969 年基线时无这些症状但感知到精神压力的女性,更有可能随后报告出现新的腹部症状(OR = 2.15,95% CI:1.39-3.34)、头痛/偏头痛(OR = 2.27,95% CI:1.48-3.48)和频繁感染(OR = 2.21,95% CI:1.12-4.36),而 1968-1969 年无精神压力的女性则无这些症状。在 37 年的随访期间,基线时感知到的精神压力与死亡率之间没有关联。
报告精神压力的女性比没有报告这些症状的女性心身症状更为常见。不在家庭以外工作和吸烟而不是低社会经济地位本身与更高的压力水平相关。感知到的高精神压力与增加的死亡率无关。